📄 Category

medicine

13473 papers

📄 medicine

Postoperative Wound Discharge After Hip Arthroplasty in Elderly Patients: Hypoalbuminemia, Not Infection, Is the Cause

This retrospective study of 32 elderly patients demonstrates that postoperative serous wound discharge following hip arthroplasty for proximal femur fractures is driven by hypoalbuminemia rather than infection, as evidenced by universally sterile cultures, the resolution of discharge with albumin supplementation, and the lack of benefit from broader antibiotic therapy for concurrent non-wound infections.

Sumit Anand¹, Chandra Shekhar Yadav¹, Nishikant Kumar²2026-10-19
📄 medicine

Prospective Evaluation of Combined Internal and External Fixation for Locked Symphysis Pubis: Clinical Outcomes and Mechanical Advantages

This prospective Level I study demonstrates that a hybrid fixation strategy combining open reduction and internal fixation with a temporary external fixator yields excellent functional outcomes and high anatomical reduction rates while effectively preventing hardware failure in patients with locked symphysis pubis.

Islam Sameeh Abdelfattah, mohamed alaa2026-10-19
📄 medicine

Joint early resuscitation-response phenotypes and post-landmark organ-support transitions in critically ill adults with acute pancreatitis: a multi-database landmark study

This multi-database landmark study identifies three distinct 24-hour early resuscitation-response phenotypes in critically ill adults with acute pancreatitis, revealing that a high-intensity phenotype characterized by concurrent fluid, vasopressor, and lactate burden is associated with subsequent organ-support escalation and delayed alive ICU discharge.

Lian-Lu Jiang, Yi Yang, Feng Liu, Pan Xiao2026-10-19
📄 medicine

Teaching and assessing surgical conscience for patient safety in perioperative teams: a scoping review of speaking up, error interception, and workplace transfer.

This scoping review argues that surgical conscience should be redefined as a teachable, observable interprofessional competency rather than an assumed virtue, proposing the VOICE-OR framework to guide curricula that progress from risk recognition to workplace safety outcomes by addressing barriers like hierarchy and fostering psychological safety.

Abel Antonio Gomez Laguna, Arley Vega Ochoa, Zoraima Romero Oñate, Anderson Díaz Pérez2026-10-19
📄 medicine

Building Trauma Care Capacity through multidisciplinary Simulation in Nepal: descriptive mixed- methods educational research

This descriptive mixed-methods study demonstrates that Nepal's first hybrid multidisciplinary trauma simulation training significantly boosted participant confidence and satisfaction while highlighting its feasibility and impact for strengthening trauma care capacity in low-resource settings.

Roshana Shrestha, Anmol Purna Shrestha, Kristopher Brickman, Heather Klepacz, Cristina Alvarado, Kristin Calkins2026-10-19
📄 medicine

Systemic inflammatory markers do not independently predict positive surgical margins after loop electrosurgical excision procedure in patients with cervical intraepithelial neoplasia grade 3: a single-center retrospective study

This single-center retrospective study of 1,373 CIN3 patients undergoing LEEP demonstrates that while a nomogram incorporating TCT grade, age, BMI, multiple HPV infection, and parity effectively predicts positive surgical margins (AUC 0.80), systemic inflammatory markers such as SIRI and NLR do not serve as independent predictors.

Jing LIU, Fengying Wu, Qiang Deng, Tingzhu Meng, Qianhui Ke, Xiyan Ouyang, Han Gao, Yanli Li, Jie Shi2026-10-19
📄 medicine

Routine Postoperative Biomarkers for Early Detection of Anastomotic Leakage After Hartmann’s Reversal: A Comparative Study

This retrospective study of 86 patients undergoing Hartmann's reversal demonstrates that routine postoperative inflammatory biomarkers, particularly the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) measured on day 3, show clinically relevant discrimination for detecting anastomotic leakage, although no single marker proved statistically superior to the others.

Daniel Ivan Astorga Guardado, Ana Jimena Iberri Jaime, Jorge De León Rendón, Joel Maya Vacio, Billy Jiménez Bobadilla, B (…)2026-10-19
📄 medicine

Intraoperative Inspired Oxygen Exposure and Mechanical Ventilation Recorded 24–48 Hours After Intracranial Neurosurgery: An INSPIRE Cohort Study

In a retrospective cohort study of 1,602 adults undergoing intracranial neurosurgery, greater intraoperative time-weighted average excess oxygen exposure was significantly associated with an increased likelihood of mechanical ventilation being recorded 24–48 hours postoperatively, though the findings do not establish causality or define a specific clinical oxygen target.

Shikun Li¹, Xu Chen¹, Rudong Chen¹, Zhuo Yang¹, Yuyang Hou¹, Jiasheng Yu¹2026-10-19
📄 medicine

A Combined Diagnostic Model for Distinguishing Mycoplasma pneumoniae Infection from Carriers in Children

This study retrospectively analyzed 1,320 children to demonstrate that a combined diagnostic model utilizing white blood cell counts, C-reactive protein levels, and clinical features effectively distinguishes genuine *Mycoplasma pneumoniae* infections from asymptomatic carriers, addressing the limitations of conventional PCR and serological tests.

Zhiyuan Lin, Minjing Cai, Hanyu You, Zhen Lin, Xianming Liang, Ping Chen2026-10-19