📄 medicine

Burnout Syndrome, sleep quality and the effect of the practice of physical activities among community pharmacists in Douala, Cameroon: A Cross-Sectional Study

This cross-sectional study of 136 community pharmacists in Douala, Cameroon, reveals a high burnout prevalence of 65.4% that is significantly associated with annual holidays and other activities, while showing no overall link between burnout and physical activity or sleep quality, though moderate physical activity was specifically linked to a higher risk of depersonalization.

Léon Jules Owona Manga, Jerson Mekoulou Ndongo, William Mbang Bian, Elysée Claude Bika Lele, Estelle Marcelle Fleurie Ng (…)2026-07-14
📄 medicine

Australian Health Professionals’ Understandings and Experiences of Broad Consent for the Future Research Use of Paediatric Genomic Data

This qualitative study of Australian health professionals reveals that broad consent for future paediatric genomic research is ethically defensible and supported when accompanied by clear explanations, robust safeguards, voluntary participation, and practices that progressively involve children as their decision-making capacity develops.

Yingyi Luo, Louise Keogh, Bernadette Richards, Monica Ferrie, Jane Nielsen2026-07-14
📄 medicine

Anticoagulation versus Antiplatelet Therapy After Cancer-Associated Ischemic Stroke: A Net-Benefit Threshold Analysis

This study uses a net-benefit threshold model to demonstrate that current randomized evidence fails to show anticoagulation provides a sufficient reduction in recurrent stroke to outweigh bleeding risks compared to antiplatelet therapy for cancer-associated ischemic stroke, thereby supporting the need for a confirmatory trial rather than a change in clinical practice.

Hyun Dong Yoo, Jae Guk Kim, Seung Young Chung2026-07-14
📄 medicine

Real-World Outcomes of Tyrosine Kinase Inhibitors in Radioactive Iodine-Refractory Differentiated Thyroid Cancer: A Cohort Study with Focus on Neoadjuvant Use

This retrospective cohort study of 35 Colombian patients with radioactive iodine-refractory differentiated thyroid cancer demonstrates that tyrosine kinase inhibitors, particularly lenvatinib, provide meaningful disease control and enable surgical resection in the neoadjuvant setting within a real-world clinical practice.

Santiago Orozco-Montoya, Guillermo Salazar-Villa, Wilfredo A. Rivera-Martínez, Carlos E. Builes-Montaño, Alejandro Román (…)2026-07-14
📄 medicine

The Lethal Convergence: Premature Mortality Surges and Widening Disparities in Concomitant Atherosclerotic Heart Disease and Heart Failure: A CDC WONDER Analysis (1999–2023)

This CDC WONDER analysis of U.S. mortality data from 1999 to 2023 reveals that while age-adjusted death rates from concurrent atherosclerotic heart disease and heart failure initially declined, they recently surged with widening disparities across gender, race, geography, and age groups, particularly alarming increases among younger adults and non-Hispanic Black populations.

Asma Chaudhary, Piyush Ratan, Pari Kotak, Mirha Imran Khan, Muhammad Shayan Tariq, Bisma Naz, Saqlain Anwar, Aisha Chaud (…)2026-07-14
📄 medicine

From "Knowing" to "Doing": Unpacking the sociocultural and systemic barriers to weight management in Chinese adults within the Greater Bay Area using the COM-B model

This qualitative study of overweight adults in China's Greater Bay Area reveals that despite high health literacy, weight management is hindered by a significant "know-do gap" driven primarily by occupational time poverty and a lack of professional guidance, necessitating a shift from individual education to system-level, AI-augmented collaborative care.

Xiaoxue Wei, Diemei Liu, Guanjun Yan, Yang Liu, Qingfeng Du2026-07-14
📄 medicine

Dengue virus at the landscape scale in Cambodia: Linking climate and land use dynamics with Dengue ecology in Southeast Asia

This four-year longitudinal study in Cambodia integrates entomological, serological, and environmental data to demonstrate that *Aedes aegypti* abundance, particularly in urban and wetland landscapes, is significantly associated with dengue incidence with a 0–4 week lag, whereas *Aedes albopictus* shows no such relationship, thereby highlighting the critical role of landscape and climate dynamics in shaping dengue transmission risks.

Sahina SIDHIK, Kimly HENG, Kimsear NOV, Sokchea LAY, Sreymom KEN, Sopheak SORN, Leangyi HENG, Y Phalla, Anavaj SAKUNTABH (…)2026-07-14
📄 medicine

Characterization of multidrug-resistant diarrheagenic Escherichia coli isolated from 2009-2020 among patients with acute diarrhea at Kisumu County Referral Hospital, Kenya

This retrospective study of 181 diarrheagenic *Escherichia coli* isolates from Kisumu, Kenya (2009–2020) reveals that Enteroaggregative *E. coli* is the predominant pathotype and that over one-third of isolates are multidrug-resistant, with high rates of resistance to first-line drugs like ampicillin and trimethoprim–sulfamethoxazole underscoring the urgent need for improved stewardship and diagnostic-guided therapy.

Christopher O. Ochieng, Abednego M. Musyoki, Fredrick Kebaso, Erick C. Kipkirui, Vanessa Natasha, Ken A. Osewe, Ibrahim (…)2026-07-14
📄 medicine

Impact of three broadcasts of a French social marketing campaign to increase parental support and physical activity of adolescents aged 11-14 years: results of a prospective cohort

A prospective cohort study of 4,005 parents demonstrates that the French "Faire bouger les ados" social marketing campaign effectively increased parental support and adolescents' physical activity, with the strongest positive impacts observed among parents who recognized all three broadcast waves compared to those with fewer exposures.

Marc Tano, Damien Tessier, Hélène Escalon, Florence Rostan, Anne-Juliette Serry, Philippine Fassier2026-07-14