13473 papers
This prospective cohort study of 442 elderly arthroplasty patients demonstrates that higher preoperative dietary fiber intake significantly reduces the risk of perioperative neurocognitive disorders, with short-chain fatty acids acting as a complete mediator in this protective gut-brain axis mechanism.
This retrospective cohort study demonstrates that an XGBoost-based machine learning model, utilizing only arterial blood gas parameters and minimal clinical features, achieves robust early prediction of retinopathy of prematurity with high sensitivity and accuracy across multiple Chinese medical institutions.
This study utilizes a disproportionality analysis of FAERS and cross-database validation in JADER to identify seven confirmed immune-related adverse events associated with pembrolizumab and nivolumab in colorectal cancer patients, demonstrating that disease-matched comparators are essential to distinguish true drug toxicity from background disease symptoms.
This case report describes an 11-year-old girl with a rare giant ileocecal inflammatory myofibroblastic tumor causing severe paraneoplastic inflammatory syndrome, which was successfully treated with complete surgical resection, leading to the rapid resolution of systemic inflammatory and hematologic abnormalities.
This sequential explanatory mixed-methods study conducted in Ethiopia reveals that nearly 69% of adults with Type 2 diabetes are non-adherent to dietary recommendations, a high rate driven by significant barriers including household food insecurity, poor dietary knowledge, lack of family support, and economic constraints.
This multicenter retrospective cohort study in China found that initiating GLP-1 receptor agonists, compared to DPP-4 inhibitors, significantly increases the risk of composite gastrointestinal adverse events in adults with type 2 diabetes, primarily driven by a twofold higher risk of gastroparesis.
This study evaluated the mineral composition and physicochemical properties of three locally prepared enteral tube feeds at Jos University Teaching Hospital, revealing significant variations in their nutritional profiles and physical characteristics that suggest a need for strategic reformulation and quality control to ensure clinical suitability.
This cross-sectional survey of 108 Community Health Workers across the Democratic Republic of the Congo, Nigeria, and Uganda reveals that while most receive regular supervision and training, gaps in drug supply, payment, and working tools significantly hinder their ability to effectively manage and refer severely ill children under Integrated Community Case Management (iCCM) programs.
This convergent parallel mixed-methods study of 539 patients in Kumasi, Ghana, reveals that while service quality perceptions vary by facility type and gender, patients' expectations consistently exceed their experiences—particularly regarding responsiveness—resulting in overall dissatisfaction with medical laboratory services.
This single-center cohort study from the United Arab Emirates reveals a dramatic increase in the incidence and prevalence of eosinophilic esophagitis between 2019 and 2024, characterizing a patient population with symptoms and demographics similar to global trends while highlighting the superior histologic response observed in patients treated with biologic therapies.