3171 papers
This contemporary study validates Hekal's "5-Not's" criteria as a reliable, high-specificity framework for identifying ideal candidates for stentless endoscopic urinary stone management, demonstrating that while the criteria effectively confirm suitability for stent-free recovery, they should not be used as an exclusive screening tool to rule out patients who fail to meet all five conditions.
This study validates a reliable and effective 10-item Spanish brief version of the Detail and Flexibility Questionnaire (DFlex) for assessing cognitive rigidity and attention to detail in individuals with eating disorders and the general population.
This multicenter observational study of 590 sarcoidosis patients reveals that those presenting with restrictive pulmonary function patterns at diagnosis exhibit more advanced radiological stages, lower DLCO values, and higher treatment needs compared to those with normal or obstructive patterns, suggesting a more severe disease course requiring closer monitoring.
This study utilizes Beta Generalized Linear Mixed Models and Random Forest algorithms on World Bank data to identify agricultural water withdrawal and access to basic drinking water as the most critical, consistent determinants of childhood wasting in West Africa, recommending targeted water management and infrastructure improvements to mitigate the issue.
This multicenter randomized clinical trial found that while an innovative outpatient palliative care day hospital model did not improve overall health-related quality of life compared to traditional clinics, it significantly reduced depression symptoms in patients with advanced cancer.
This study of 384 food handlers in Jalalabad, Afghanistan, reveals that while food safety knowledge, attitudes, and practices are generally moderate to good, the overall hygienic status of food establishments is poor, highlighting a critical need for enhanced monitoring and comprehensive training programs to improve compliance.
This study demonstrates that disulfiram, particularly at a 10 mg/kg dose, significantly attenuates paraquat-induced renal injury and fibrosis in rats by mitigating oxidative stress and rebalancing the Smad3/Smad7 signaling axis, highlighting its potential as a repurposed therapeutic agent for pesticide-induced kidney damage.
This study found that while digital assessment of dental cavity preparations using Exocad shows good reliability compared to expert grading, it systematically yields lower scores—particularly for marginal ridge thickness—suggesting a hybrid model of digital screening followed by expert review is optimal for preclinical education.
This cross-sectional study conducted in Kabul, Afghanistan, reveals a 14.1% COPD prevalence among patients, identifying winter seasonality, indoor air pollution, passive smoking, and high rates of comorbidities as key risk factors that necessitate targeted public health interventions.
This qualitative study of 39 Australian interviews identifies universal barriers and facilitators to postnatal care guideline implementation while highlighting that the new national living guideline model introduces unique challenges, such as managing clinician 'change fatigue' and ensuring methodological awareness, which require tailored local strategies to optimize clinical outcomes.