📄 Category

medicine

13473 papers

📄 medicine

Co-designing an intersectoral learning community to address the needs of people living with obesity: a participatory mixed-methods study in a semi- rural region of Quebec, Canada

This participatory mixed-methods study in semi-rural Quebec demonstrates that while co-designing an intersectoral learning community successfully strengthened relational and cognitive foundations for collaboration among diverse stakeholders to address obesity, the initiative has not yet achieved fully integrated collective action due to challenges in strategic representation, governance, and resource allocation.

Blandine Lentilhac, Marguerite Boudrias, Audrey L’Espérance, Laurence Berthelet, Anne Schweitzer, Nadia Sourial, Jean-Ba (…)2026-10-19
📄 medicine

Machine learning-based prediction of mortality and renal replacement therapy in ANCA- associated vasculitis: a single-center cohort study

This single-center cohort study demonstrates that machine learning models, particularly random forest for mortality and XGBoost for renal replacement therapy, effectively predict adverse outcomes in ANCA-associated vasculitis patients by identifying advanced age, dialysis requirement at diagnosis, and low eGFR as key independent risk factors.

Liepeng Chu, Binglan Yang, Lizhen Li, Fengyuan Xu, Bingyuan Nong, Chao Xue2026-10-19
📄 medicine

Kidney transplantation and too-sick removal among waitlisted candidates with prior malignancy: a retrospective OPTN/UNOS cohort study, 2000– 2026

This retrospective cohort study of nearly one million US kidney transplant candidates found that, among those already waitlisted, a recorded prior malignancy is associated with a modestly higher five-year probability of transplantation—driven by increased living-donor transplants—alongside a higher risk of removal due to being too sick.

Hongyu Zhang, Yin Lu, Zexuan Lv, Xinhang Wu, Fan Gao, Qiang Cheng, Yi Feng, Bin Jiang, Jinlu Tang, BingYang Guo, Qing Ai (…)2026-10-19
📄 medicine

Association Between Early Plasma Transfusion Burden and Mortality and Infection-Associated Organ Dysfunction in Severe Trauma Patients: A Single-Center Retrospective Exploratory Study

This single-center retrospective exploratory study of 100 severe trauma patients suggests a preliminary association between early 24-hour plasma transfusion volume and increased 30-day mortality risk, while finding no significant link between transfusion burden or injury severity and early infection-associated organ dysfunction, though the small sample size necessitates validation in larger prospective trials.

Ziyun Li, Junyan Wang, Zhoubo Wang, Yuechuan Shen2026-10-19
📄 medicine

Thenar Muscle Thickness Assessed by Point-of-Care Ultrasound and Geriatric Vulnerability in Hospitalized Older Adults: A Pilot Study

This pilot study of 50 hospitalized adults aged 75 and older found that greater thenar muscle thickness, measured via point-of-care ultrasound, is significantly associated with better nutritional status and lower risks of pressure injuries and falls, suggesting its potential utility as a pragmatic marker for geriatric vulnerability despite the study's small sample size and lack of a sarcopenia reference standard.

Nelson Anzoletti, Michela Giansante, Claudia Paolini, Lucia Fasciani, Andrea Boccatonda, Alessia Di Lorito, Giulio Cocco (…)2026-10-19
📄 medicine

When tiny lungs Struggle to breathe; a rare cause of Refractory Primary Pulmonary Hypertension

This paper presents a fatal case of a 2-day-old infant with refractory primary pulmonary hypertension, ultimately diagnosed post-mortem as Alveolar Capillary Dysplasia with Malpositioned Pulmonary Veins (ACD/MPV), highlighting the critical need for clinical suspicion and thoracic pathology expertise to identify this rare and lethal congenital disorder.

Monica Sivakumar, Donna C Philip, Maria Frances Bukelo2026-10-19
📄 medicine

Prenatal Education Needs and Preferences by Educational Attainment Among Pregnant Patients: A Prospective, Cross-sectional Observational Study

This prospective cross-sectional study reveals that while pregnant patients across all educational backgrounds share a similar high interest in prenatal education, those with lower educational attainment prioritize different informational topics—specifically normal pregnancy changes and labor induction—highlighting the need to individualize counseling content based on educational level.

Zoe Keese, Rebecca Anderson, Rachel Weber, Heather Ramsey, Mridula Ghotane, Santiago Ortiz Barragan, Rebecca Rimsza2026-10-19
📄 medicine

Primary Extramedullary Plasmacytoma of the Ileum: A Rare Diagnostic Challenge with Clinicopathological Correlation and Review of the Literature

This paper presents a rare case of primary extramedullary plasmacytoma in the ileum of a 40-year-old patient, highlighting the diagnostic challenges posed by its non-specific symptoms and imaging features, and emphasizing the necessity of histopathological confirmation with immunohistochemistry and systemic workup to differentiate it from other neoplasms and rule out multiple myeloma.

Anurag Singh, Akansha Singh, Akansha Rastogi, Prachi Chaudhary, Rahul Rahul, Surya Kant, Pallavi Prasad2026-10-19