13473 papers
This case report illustrates that secondary syphilitic hepatitis can mimic autoimmune liver disease through overlapping cholestatic biochemistry and positive autoantibodies, highlighting the critical importance of syphilis testing to avoid inappropriate immunosuppression and ensure resolution with antimicrobial therapy.
This prospective observational study of 40 breath-hold divers demonstrates that prolonged dry static apnea induces a significant, rapid-onset increase in intraocular pressure that correlates with elevated blood pressure and decreased oxygen saturation, likely driven by increased episcleral venous pressure, followed by immediate normalization upon resumption of breathing.
In patients with acute coronary syndrome, admission Tpeak–Tend interval and Tp-e/QTc ratio correlate with angiographic and clinical severity, with the Tp-e/QTc ratio serving as an independent predictor of six-month adverse outcomes that enhances the prognostic accuracy of the GRACE score.
While AI-generated feedback for informed consent training was rated as higher quality and more comprehensive than surgeon-generated feedback, the AI systematically assigned more favorable performance scores, indicating that high feedback quality does not guarantee evaluative validity and highlighting the need for human oversight in nuanced surgical assessments.
This prospective cohort study of 148 patients undergoing chemotherapy with corticosteroids found that steroid-induced hyperglycemia is common, particularly in those with pre-existing diabetes, and that 12% of non-diabetic patients developed steroid-induced diabetes by week 12, highlighting the need for universal nurse-led blood glucose monitoring and management.
This retrospective MIMIC-IV study demonstrates that while linked electronic health records can partially operationalize components of the Fifth Universal Definition of Myocardial Infarction, significant gaps in data availability—particularly regarding ECG reports, imaging, and adjudication—limit the feasibility of fully retrospective evaluation without local prospective verification.
This cross-sectional survey of 138 orthodontists reveals that while localized intraoral characteristics in borderline cases significantly influence which premolar is selected for extraction, the overall decision to extract remains relatively stable and is more strongly associated with the clinician's preference for fixed buccal appliances versus clear aligners.
This single-center study in Japan reveals that while over 90% of oncology healthcare providers recognize patient interest in reproductive options for cancer predisposition syndromes, only 20% are actually aware of Preimplantation Genetic Testing for Monogenic Disorders (PGT-M), highlighting an urgent need for improved provider education and support systems.
This study of 404 infants with feeding problems reveals that the morphological subtypes of ankyloglossia shift significantly with age—specifically, a decrease in anterior membrane types and an increase in tower types—suggesting structural remodeling rather than simple elongation and indicating that delaying surgical intervention in anticipation of spontaneous improvement may be inappropriate.
This retrospective study demonstrates that the ranking of four RAG-enabled LLMs for oral squamous cell carcinoma treatment planning varies significantly depending on the evaluation metric used, highlighting the limitations of relying on single aggregate scores to determine clinical model performance.