3171 papers
This study demonstrates that genipin effectively ameliorates experimental rheumatoid arthritis in rats by suppressing pro-inflammatory cytokines and hematological abnormalities while promoting anti-inflammatory responses, a mechanism supported by molecular docking and favorable ADMET profiles.
This study of female volleyball athletes reveals that knee pain risk is significantly driven by the interaction between specific mobility deficits (particularly foot posture and dorsiflexion range of motion) and strength limitations, where the combination of these factors creates a substantially higher likelihood of pain than either deficit alone.
This case–control study of a Libyan population identifies Factor V Leiden and Factor V H1299R polymorphisms as significant genetic risk factors for coronary artery disease, while finding no statistically significant association with the Prothrombin G20210A variant.
This study reveals that while absolute rates remain low, constipation-associated mortality in the United States has significantly increased since 2012, disproportionately affecting older adults, women, and non-metropolitan residents, with the rise driven by downstream complications rather than underlying causes or substance use disorders.
This study identifies high tumor GPR40 expression as an independent adverse prognostic marker for overall survival in metastatic hormone-sensitive prostate cancer, whereas GPR120 expression, while associated with shorter survival in univariate analysis, lacks independent predictive value.
This study presents an interpretable machine learning framework that integrates multimodal preoperative physiologic data to generate a clinically deployable risk score for accurately predicting new-onset postoperative dysphagia following anti-reflux surgery.
This study demonstrates that an interpretable logistic regression model using five key clinical predictors can effectively stratify Type 2 diabetes risk with 77.5% accuracy, offering a transparent alternative to complex black-box algorithms for clinical decision support.
This paper details the design, implementation, and real-world deployment of HALO-X, a specialized remote patient monitoring platform for cancer care that successfully integrated multi-modal biometric and questionnaire data across three clinical studies to differentiate patient outcomes while addressing key challenges in cost, interoperability, and clinical adoption.
This paper reports a rare case of a congenital accessory posterior cerebral artery (PCA) arising from the internal carotid artery and anastomosing with the normal PCA just distal to the P1-P2 junction, a variant that was successfully identified through careful analysis of magnetic resonance angiography source images and partial maximum-intensity-projection reconstructions.
This paper reports a rare case of severe terbinafine-induced gastritis presenting as protein-losing enteropathy in a patient with POEMS syndrome, which resolved upon discontinuation of the drug and highlights the need to consider medication-induced gastritis when common causes are excluded.