📄 medicine

Kidney transplantation and too-sick removal among waitlisted candidates with prior malignancy: a retrospective OPTN/UNOS cohort study, 2000– 2026

This retrospective cohort study of nearly one million US kidney transplant candidates found that, among those already waitlisted, a recorded prior malignancy is associated with a modestly higher five-year probability of transplantation—driven by increased living-donor transplants—alongside a higher risk of removal due to being too sick.

Hongyu Zhang, Yin Lu, Zexuan Lv, Xinhang Wu, Fan Gao, Qiang Cheng, Yi Feng, Bin Jiang, Jinlu Tang, BingYang Guo, Qing Ai (…)2026-10-19
📄 medicine

Association Between Early Plasma Transfusion Burden and Mortality and Infection-Associated Organ Dysfunction in Severe Trauma Patients: A Single-Center Retrospective Exploratory Study

This single-center retrospective exploratory study of 100 severe trauma patients suggests a preliminary association between early 24-hour plasma transfusion volume and increased 30-day mortality risk, while finding no significant link between transfusion burden or injury severity and early infection-associated organ dysfunction, though the small sample size necessitates validation in larger prospective trials.

Ziyun Li, Junyan Wang, Zhoubo Wang, Yuechuan Shen2026-10-19
📄 medicine

Thenar Muscle Thickness Assessed by Point-of-Care Ultrasound and Geriatric Vulnerability in Hospitalized Older Adults: A Pilot Study

This pilot study of 50 hospitalized adults aged 75 and older found that greater thenar muscle thickness, measured via point-of-care ultrasound, is significantly associated with better nutritional status and lower risks of pressure injuries and falls, suggesting its potential utility as a pragmatic marker for geriatric vulnerability despite the study's small sample size and lack of a sarcopenia reference standard.

Nelson Anzoletti, Michela Giansante, Claudia Paolini, Lucia Fasciani, Andrea Boccatonda, Alessia Di Lorito, Giulio Cocco (…)2026-10-19
📄 medicine

When tiny lungs Struggle to breathe; a rare cause of Refractory Primary Pulmonary Hypertension

This paper presents a fatal case of a 2-day-old infant with refractory primary pulmonary hypertension, ultimately diagnosed post-mortem as Alveolar Capillary Dysplasia with Malpositioned Pulmonary Veins (ACD/MPV), highlighting the critical need for clinical suspicion and thoracic pathology expertise to identify this rare and lethal congenital disorder.

Monica Sivakumar, Donna C Philip, Maria Frances Bukelo2026-10-19
📄 medicine

Prenatal Education Needs and Preferences by Educational Attainment Among Pregnant Patients: A Prospective, Cross-sectional Observational Study

This prospective cross-sectional study reveals that while pregnant patients across all educational backgrounds share a similar high interest in prenatal education, those with lower educational attainment prioritize different informational topics—specifically normal pregnancy changes and labor induction—highlighting the need to individualize counseling content based on educational level.

Zoe Keese, Rebecca Anderson, Rachel Weber, Heather Ramsey, Mridula Ghotane, Santiago Ortiz Barragan, Rebecca Rimsza2026-10-19
📄 medicine

Primary Extramedullary Plasmacytoma of the Ileum: A Rare Diagnostic Challenge with Clinicopathological Correlation and Review of the Literature

This paper presents a rare case of primary extramedullary plasmacytoma in the ileum of a 40-year-old patient, highlighting the diagnostic challenges posed by its non-specific symptoms and imaging features, and emphasizing the necessity of histopathological confirmation with immunohistochemistry and systemic workup to differentiate it from other neoplasms and rule out multiple myeloma.

Anurag Singh, Akansha Singh, Akansha Rastogi, Prachi Chaudhary, Rahul Rahul, Surya Kant, Pallavi Prasad2026-10-19
📄 medicine

First-line treatment of non-haemorrhagic early miscarriage in gynaecological emergencies in public hospitals on Reunion Island in 2022

A 2022 cross-sectional study of public hospitals in Reunion Island found that non-surgical management (primarily expectant or pharmacological) was the preferred first-line treatment for the vast majority of patients with non-haemorrhagic early miscarriage, suggesting a need to expand out-of-hospital care networks.

Pierric GIROU, Marion LAVILLE, Laura MATARD, Laurie SAVARY, Sébastien LERUSTE, Éric BERTRAND, Jessica DUMEZ2026-10-19