3171 papers
This study reviews 100 adult lower gastrointestinal perforation cases to highlight the diagnostic challenges and specific histopathological criteria required to accurately identify the rare condition of segmental absence of intestinal musculature (SAIM) and distinguish it from mimics like diverticular disease and ischemia.
This study demonstrates that menopause status significantly differentiates how cardiometabolic risk factors, such as systolic blood pressure and total cholesterol, relate to resting-state functional connectivity patterns in middle-aged females, with specific associations varying by menopausal stage despite neither pattern predicting spatial memory performance.
This exploratory multicentre study found that diabetes is an independent predictor of poorer ICSI outcomes in patients with retrograde ejaculation, while numerical trends suggesting superior results with testicular versus ejaculated sperm require confirmation through larger prospective studies.
This pan-cancer analysis reveals that overexpression of Replication Protein A (RPA) genes is associated with poor prognosis, an immunosuppressive tumor microenvironment, and weak immunotherapeutic response in Lower-Grade Glioma and Liver Hepatocellular Carcinoma, while simultaneously indicating susceptibility to targeted drugs like doxorubicin, thus positioning RPA as a promising prognostic and therapeutic biomarker for these cancers.
This cross-sectional study at the University of Health and Allied Sciences in Ghana reveals that medical students possess significantly higher awareness and knowledge of ototoxic medications compared to allied health students, highlighting a critical need for targeted educational interventions to address these disparities and improve future patient safety.
This cross-sectional study of female university students in Lebanon and Armenia reveals that unhealthy toileting behaviors are significantly associated with overactive bladder symptoms in both populations, though specific behavioral patterns like delayed voiding in Lebanon and premature voiding in Armenia show distinct country-specific correlations.
This cross-sectional study conducted at Ayder Comprehensive Specialized Hospital in Ethiopia found that 38.9% of patients on Dolutegravir-based first-line antiretroviral therapy reported adverse drug reactions, with urban residence, earlier disease stage at initiation, treatment-naïve status, and concomitant medication use identified as significant associated factors.
This study presents a smart, dual-responsive hydrogel microsphere that delivers a MEK inhibitor and citric acid in a temporally controlled sequence to suppress the ETS2/c-Jun inflammatory axis and reprogram the degenerative nucleus pulposus microenvironment, thereby achieving functional intervertebral disc regeneration.
This study estimates population-specific dietary iron requirements for the Saudi population using a factorial modeling approach based on physiological losses, local body weight data, and varying bioavailability levels to inform nutritional policy and assessment.
This study of older Indian adults demonstrates that intrinsic capacity and the physical frailty phenotype are complementary rather than redundant predictors of mortality, with cognitive function specifically identifying high-risk individuals who appear physically robust but would otherwise be missed by frailty screening alone.