📄 medicine

‘One shunt fits all?’: A comparative laboratory study of antibiotic- impregnated shunt catheters with retrospective clinical correlation

This study reveals significant product-specific biochemical and physical variations among commercially available antibiotic-impregnated shunt catheters, with retrospective data linking the Ares® brand to a significantly higher incidence of unexplained abdominal pain compared to Bactiseal®, suggesting that catheter selection may impact clinical outcomes despite the need for further prospective validation.

Kanza Tariq, Mehran Moazen, Anastasiia Maliuk, Celine Krista Vicedo, Simon Thompson, Linda D’Antona, Jesvin Sunny, Gilli (…)2026-10-20
📄 medicine

Knowledge, attitudes and human papillomavirus vaccine recommendation practices among primary care physicians in Bahrain: a cross-sectional study

A 2025 cross-sectional study of 205 primary care physicians in Bahrain reveals that while most possess strong knowledge and positive attitudes toward the HPV vaccine, regular recommendation practices are driven by clinical experience and perceived parental acceptance rather than knowledge levels, largely due to the vaccine's delivery via school campaigns limiting routine physician opportunities.

Fatema A. Yusuf, Maryam A. Ahmed, Zahraa A. Alali, Zakeya S. Khalaf, Riham Algarf, Muna A. Almohri, Basheer Makarem, Sad (…)2026-10-20
📄 medicine

Calcium-Free Predilution for Circuit Preservation During CRRT Without Routine Anticoagulation: A Single-Center ICU Pilot Study 

This single-center pilot study demonstrates that a calcium-free predilution strategy serves as a feasible rescue approach for maintaining circuit patency during continuous renal replacement therapy in critically ill patients when standard anticoagulation is contraindicated or unavailable, achieving acceptable filter survival without causing uncontrolled metabolic complications.

can colakoglu2026-10-20
📄 medicine

Primary Headache Disorders in Adolescents: Phenotypic Patterns and Multidimensional Burden on Quality of life and Psychosocial Well-being -part I

This cross-sectional study of Georgian adolescents reveals that while frequent and severe primary headaches significantly impair physical energy, social functioning, and academic performance, family dynamics appear to buffer against generalized anxiety and preserve subjective happiness.

tamar malkhaz bitskinashvili, Nana Nino Tatishvili2026-10-20
📄 medicine

Sex differences in pregnancy complications and autism

This study utilizing Swedish birth registry data reveals that while male pregnancies are generally more prone to complications, the link between these complications and autism is largely independent of fetal sex, with prematurity and other factors consistently associated with autism across both sexes, ultimately identifying fetal sex as the strongest predictor of autism likelihood.

Alex Tsompanidis, Johanna Sieurin, Cecilia Magnusson, Simon Baron-Cohen, Kyriaki Kosidou2026-10-20
📄 medicine

Postpartum Depressive Symptoms and Associated Risk Factors Among Women Undergoing Caesarean Delivery at a Tertiary Care Centre in New Delhi, India: A Prospective Observational Study

This prospective observational study of 350 women in New Delhi undergoing caesarean delivery found that postpartum depressive symptoms were prevalent (18.3% over six months) and significantly associated with risk factors including family history of psychiatric illness, intimate partner violence, lack of social support, multiparity, elective caesarean delivery, and postoperative complications, underscoring the need for integrated screening and targeted mental health support in postnatal care.

Shweta Varun, Pratima Mittal, Rekha Bharti, Bhagyashree Singh, Garima Singh, Pankaj Verma, Abhishek Lachyan2026-10-20
📄 medicine

Study protocol for a hybrid type III effectiveness-implementation evaluation of the Detecta-APS strategy for organized breast and cervical cancer screening in Brazilian primary health care

This study protocol outlines a hybrid type III effectiveness-implementation evaluation using a multi-methods design to assess the DETECTA-APS strategy's role in transitioning Brazil's primary health care from opportunistic to organized breast and cervical cancer screening, with the goal of identifying implementation determinants and informing context-sensitive adaptations to improve access and outcomes.

Talita dos Santos Rosa, Andressa Rocha Olah, Ilana Eshriqui Oliveira, Leticia Yamawaka de Almeida, Talita Rewa, Marilia (…)2026-10-20
📄 medicine

Socioeconomic status and high impact chronic pain among adults in the United States: analysis of the 2016 National Health Interview Survey

This cross-sectional analysis of the 2016 National Health Interview Survey reveals that lower socioeconomic status is independently associated with significantly higher odds of high-impact chronic pain among U.S. adults, highlighting the need for interventions that address educational, employment, and poverty-related inequalities alongside clinical management.

Korin Neh Nforbi, Isaac Obeng Gyasi, Bibiana Frans-Asmah, Philip Obiri Ankomah, Susan Onumanyiwa Nyanteh, Abigail Obeng (…)2026-10-20