📄 medicine

Exploring Midwives’ Experiences with Intrapartum Care in Health Facilities in Ankole Sub-region, South Western, Uganda

This qualitative study of midwives in Uganda's Ankole Sub-region reveals that while they possess a strong professional drive, their intrapartum care delivery and career retention are significantly compromised by systemic limitations, resource shortages, and heavy workloads that lead to burnout and dissatisfaction.

Eve Katushabe, Mary Steen, Ayishetu Musa-Maliki2026-07-13
📄 medicine

Calibrated within-population patient individualisation of antimicrobial exposure: a pre-registered simulation and external-evaluation study

This pre-registered simulation and external-evaluation study demonstrates that a model-informed precision dosing engine, utilizing a compiled medical-knowledge substrate, successfully provides calibrated, unbiased, and more accurate within-population individualized dosing for narrow-therapeutic-index antimicrobials across diverse critical-care populations.

Youssef Ghaly2026-07-13✓ Author reviewed
📄 medicine

Developing a School-based Mindfulness Intervention for Delivery in Rwanda and Ethiopia: Cultural Adaptation through Knotworking

This qualitative study details the co-creation of a culturally adapted, school-based mindfulness intervention for Rwanda and Ethiopia through a collaborative "knotworking" process that addressed local constraints like large class sizes and religious sensitivities to develop a feasible curriculum for low-resource settings.

Rachel Shanks, Stephanie Thomson, Charlaine Simpson, Pamela Abbott2026-07-13
📄 medicine

Nanoparticle-Mediated Modulation of the PINK1/Parkin Mitophagy Pathway in Parkinson’s Disease: A Scoping Review

This scoping review highlights the potential of nanoparticle-based delivery systems to overcome blood-brain barrier limitations and modulate the PINK1/Parkin pathway for Parkinson's disease treatment, while noting that current evidence is extremely limited to a single study and calls for more standardized research to validate clinical efficacy.

Clare Kingsley, Nicole Ahad, Kaleb Rodriguez, Alexa Q. Xiang2026-07-13
📄 medicine

Ownership–Utilization Gap in Long-Lasting Insecticidal Net Use Among Pregnant Women in Bonsu Sub-Municipality, Ghana: A Cross-Sectional Study

Despite near-universal ownership of long-lasting insecticidal nets among pregnant women in Bonsu Sub-Municipality, Ghana, a significant utilization gap persists primarily due to knowledge deficits regarding insecticide efficacy and physical discomfort from side effects, rather than supply-side barriers.

Richmond Yaw Osei, Ishmael Awini Aburi, Abigail Boatemaa, Baffour Osei, Gabriel Osei Forkuo2026-07-13
📄 medicine

Where Are Our Physicians? Mapping the distribution of medical schools, training hospitals, and social health insurance accredited physicians in the Philippines

This study reveals that the Philippines' PhilHealth-accredited physician workforce is critically insufficient and heavily concentrated in the National Capital Region, with a distribution pattern mirroring that of medical schools and training hospitals, leaving dozens of provinces without access to essential specialist care.

Ryan Gabriel C. Molen, Veincent Christian F. Pepito, Hazel Ivy M. Jeremias, Ann Rose D. Payumo, Theo Prudencio Juhani Z. (…)2026-07-13
📄 medicine

Socioeconomic Disparities in Telemedicine Use and High-Need Nonuse Among Older Adults With Multimorbidity: A Cross-Sectional Analysis of NHANES August 2021–August 2023

This cross-sectional analysis of NHANES data reveals that while telemedicine use among older adults with multimorbidity is associated with both clinical need and socioeconomic resources, lower income significantly increases the likelihood of high-need nonuse, highlighting persistent disparities in access to remote care.

Yan Zou, Shan Hui2026-07-13
📄 medicine

Beyond Trans Fats: Operationalizing Codex NRV-NCD Standard and Comparative Predictive Cardiovascular Risk Modeling for Refined Palm Olein Policy in Nigeria

This paper argues that Nigeria's unregulated high-saturated-fat palm olein market poses a severe cardiovascular threat and proposes a dual regulatory strategy combining mandatory compositional reformulation (capping SFAs at 35 g/100 g or lower) with volumetric consumption limits to significantly reduce ischemic heart disease risk across the population.

CHRISTOPHER ENASOR FREGENE, Dike Bevis Ojji, Abimbola Opeyemi Adegboye2026-07-13
📄 medicine

Hepatitis B virus in Pakistan: serological marker prevalence, clinical correlates, and genotype-informed interpretation

This study analyzes serological markers, clinical characteristics, and treatment outcomes in a Pakistani cohort with hepatitis B virus, revealing a 1.85% HBsAg prevalence with a significant active-replication subgroup, and underscores the urgent need for enhanced vaccination, early diagnosis, and genotype-informed surveillance to manage chronic HBV in Pakistan.

Muhammad Rehan Uppal, Rizwan Uppal, Umar Saeed, Muhammad Saad Uppal, Aftab Ahmed Khan, Zahra Zahid Piracha2026-07-13