📄 medicine

Percutaneous Endoscopic Interlaminar Discectomy For Lumbar Disc: Early Experience, Outcome and Complication: a Retrospective Observational Study With a Pre–Post Design

This retrospective observational study of 41 patients at H. Adam Malik General Hospital demonstrates that Percutaneous Endoscopic Interlaminar Discectomy (PEID) is a safe and effective minimally invasive treatment for lumbar disc herniation, significantly reducing pain and improving physical function with a low complication rate.

Sabri Ibrahim, Muhammad Deni Nasution, Muhammad Fahmi Rasyid2026-07-13
📄 medicine

An Open, Reproducible Implementation of the CMS Hospital-Wide Readmission Measure on MIMIC-IV

This paper presents an open, reproducible reference implementation of the clinically accurate CMS Hospital-Wide Readmission measure on MIMIC-IV, demonstrating that faithfully applying its complex exclusion and stratification rules significantly alters the prediction target compared to naive definitions while providing a calibrated baseline model and resources for fair, leakage-controlled research.

Sai Sharan Kasa2026-07-13
📄 medicine

Real-World Event-Free Survival and Real-World Pathological Complete Response in Early-Stage Triple-Negative Breast Cancer: Concordance with Estimates from the control arm of the KEYNOTE-522 Trial

This retrospective study demonstrates that real-world event-free survival and pathological complete response rates for early-stage triple-negative breast cancer are concordant with the control arm estimates from the KEYNOTE-522 clinical trial, confirming the replicability of trial outcomes in matched real-world populations.

Carole R. Berini, Jessica K. Paulus, Malcolm Charles, Zhaohui Su, Paul Conkling, Jagadeswara Rao Earla, Amin Haiderali (…)2026-07-13
📄 medicine

Development of a Telemedicine Platform with Artificial Intelligence-Assisted Care Diary for Rare Disease Management

This study presents the development and pilot testing of a specialized telemedicine platform in Korea that integrates AI-assisted care diaries, multi-party video consultations, and adherence tracking to improve accessibility and care coordination for patients with rare diseases and their families.

Youngshin Joo, Jisoo Baek, Jong-Hee Chae, Soo Yeon Kim, Seungbok Lee, Taehyeong Park, Gilmook Choi, Yong Jin Kwon2026-07-13
📄 medicine

Baloxavir and molnupiravir protect against severe influenza A(H5N1) infection in immunosuppressed hamsters

This study demonstrates that baloxavir, high-dose molnupiravir, and combination therapies effectively protect immunosuppressed hamsters against severe A(H5N1) infection by reducing viral burden and preventing neuroinvasion, highlighting their potential as critical treatments for vulnerable populations during a pandemic.

Mariana Baz, Andrea Arroyave, Henintsoa Rabezanahary, Ahmed Sahli2026-07-13
📄 medicine

Concordance Between Molecular Techniques (like Multiplex PCR/BioFire) and Traditional Cultures – A Review

This review demonstrates that molecular diagnostic techniques like multiplex PCR and BioFire FilmArray systems exhibit high concordance with traditional culture methods while offering significantly faster turnaround times and improved detection of pathogens, particularly in patients previously treated with antibiotics, thereby enhancing clinical decision-making and antimicrobial stewardship.

Sahil Langde, Khushbu Agarwal, Shirish Karni, Abhishek Lachyan2026-07-13
📄 medicine

Hip strength ratios and trunk-pelvis coordination during the soccer inside kick: a 1D-SPM analysis

This study demonstrates that velocity-specific, multi-planar hip strength imbalances in male soccer players are significantly associated with distinct, phase-specific trunk-pelvis and lower-limb coordination patterns during the inside kick, supporting the use of combined strength profiling and waveform analysis to characterize movement strategies relevant to groin loading.

Tomonari Sugano, Ryo Kuboshita, Toru Tanabe, Nobuhide Azuma, Seigaku Hayashi, Masahito Hitosugi2026-07-13