📄 medicine

Cervical Er:YAG Laser in Low-Risk CIN Management: A Promising Option Compared to Expectant Management and Conservative Treatments — A Pilot Study

This pilot study demonstrates that cervical Er:YAG laser treatment yields superior colposcopic regression and HPV clearance rates compared to silicon dioxide-based vaginal gel in managing low-risk cervical dysplasia, while also offering a more immediate resolution than expectant management despite a small risk of progression in the latter group.

Suleyman Engin Akhan, Egemen Koyuncu, İpek Evruke, İnci Sema Tas, Sibel Balci, Cenk Yasa2026-07-12
📄 medicine

Burden, Patterns, and associated factors of post-kidney transplant infections among renal transplant recipients in Ethiopia: a retrospective study

This retrospective study of 203 kidney transplant recipients in Ethiopia reveals a high burden of post-transplant infections, predominantly bacterial and most frequent within the first year, with residence in Addis Ababa identified as a significant associated factor.

Hiwot Beyene Mengistu, Absalat Serawit Negussie, Azeb Kebede Woldetsadik, Ayantu Tesfaye Lemma, Addisu Melike Ejigu, Won (…)2026-07-12
📄 medicine

Economic evaluation of topical ketorolac and nepafenac prophylaxis for early-stage retinopathy of prematurity: a multicenter real-world study in Colombia

This multicenter real-world study in Colombia found that while topical ketorolac and nepafenac prophylaxis for early-stage retinopathy of prematurity were associated with lower costs and, in the case of ketorolac, higher quality-adjusted life-years compared to surveillance alone, the results do not yet support routine adoption and highlight the need for well-powered randomized trials.

Marudys Stella Mestra Burgos, Giliana García-Acevedo, Jorge Eduardo Silva Moreno, Karol Valeria Guerrero Beltrán, Wilman (…)2026-07-12
📄 medicine

Electro-acupuncture combined with adjuvant chemotherapy in gastric cancer (EAGER-2): a protocol for a multicenter randomized controlled trial

The EAGER-2 study is a multicenter, participant-blinded, sham-controlled randomized trial designed to validate the efficacy of electro-acupuncture combined with adjuvant chemotherapy in improving disease-free survival and other clinical outcomes for gastric cancer patients following gastrectomy.

Yuxing Hu, Xuesong Chang, Xiaoshu Chai, Ziyan He, Jiaming Liu, Zexing Zhang, Tianlin Wang, Yadong Chen, Yihan He, Yanjua (…)2026-07-12
📄 medicine

Dietary and chemical factors concurrently related to overweight in children and young adults – A cross-sectional Exposome-Wide Association Study (ExWAS)

This cross-sectional ExWAS study of over 41,000 US individuals aged 2–25 identified 91 dietary and chemical exposures associated with overweight, highlighting that while most consistent factors were linked to lower odds (such as fiber, copper, and folates), few were consistently associated with higher odds (notably gamma tocopherol and cotinine).

Anne Kristine Christensen, Cecilia Ramlau-Hansen, Thorkild Sorensen, Olivier Jolliet, Christina Dahm2026-07-12
📄 medicine

Unveiling the Biomechanics of a Novel Distalizer Appliance: Finite Element Analysis of Stress Distribution and Molar Displacement Running title: Biomechanical Evaluation of a Novel Distalizer

This study utilizes Finite Element Analysis to demonstrate that a novel palatal TAD-supported distalizer applying equal forces to both the first and second maxillary molars yields more uniform stress distribution, greater bodily displacement, and superior vertical control compared to an appliance applying force solely to the first molar.

Mostafa K. Sofar, Mushriq Abid2026-07-12
📄 medicine

Prognostic differences of refractory/relapsed diffuse large B-cell lymphoma with bulky and non-bulky disease in the chimeric antigen receptor T cell therapy era

In the CAR-T therapy era, patients with bulky relapsed/refractory diffuse large B-cell lymphoma experience worse overall survival compared to non-bulky patients, though the combination of autologous hematopoietic stem cell transplantation and CAR-T significantly improves outcomes for both groups.

Xiying Huang, Dongliang Zhang, Guihua Lu, Xiong Ni, Gusheng Tang, Libing Wang, Wenqin Yue, Li Chen, Jie Chen, Tao Wang (…)2026-07-12
📄 medicine

Atrial distensibility predicts short-term prognosis in fetal single ventricle-type congenital heart disease with atrioventricular valve regurgitation

This study demonstrates that quantitative assessment of atrial distensibility is a significant predictor of short-term perinatal adverse outcomes in fetuses with single ventricle-type congenital heart disease and moderate-to-severe atrioventricular valve regurgitation.

Yohei Akazawa, Kosuke Yonehara, Haruka Obinata, Ryusuke Numata, Yuma Shibuya, Kohta Takei, Kiyohiro Takigiku2026-07-12