3171 papers
This study demonstrates that implementing clinical pharmacy services, specifically medication reviews and pharmaceutical interviews, in a pediatric cardiology department is feasible and effective in identifying significant medication-related problems and enhancing the safe use of high-risk medications for vulnerable young patients.
This retrospective cohort study in South Africa reveals that while socioeconomic status does not directly predict laryngotracheal stenosis outcomes, it significantly influences the etiology of the disease, which in turn mediates clinical severity and treatment success through a mechanism termed "aetiological embedding of social determinants."
This study introduces and validates the CT-based SPA-CE classification system for glenoid bone loss in reverse shoulder arthroplasty, demonstrating its utility as a treatment-oriented framework that correlates specific defect patterns with appropriate reconstructive strategies and offers greater morphological detail than existing systems like Walch.
This study demonstrates that the expression of neutrophil extracellular trap (NET) components (CitH3, MPO, and NE) in colonic mucosa is significantly elevated in pediatric Crohn's disease and positively correlates with disease activity, suggesting their potential as biomarkers for assessing disease severity.
This single-center retrospective study of 186 patients undergoing general anesthesia found that a lower minimum intraoperative perfusion index (PI min) is significantly associated with end-of-surgery hyperlactatemia, suggesting PI min may serve as a simple marker for hypoperfusion-related metabolic stress despite its modest discriminative performance.
This prospective single-arm study of 12 Saudi patients demonstrates that radiofrequency ablation turbinate reduction is an effective treatment for rhinitis medicamentosa, successfully enabling complete decongestant withdrawal and significantly improving nasal obstruction and quality of life.
This global study utilizing large language models to analyze free-text survey responses from over 3,700 unvaccinated individuals reveals that COVID-19 vaccine refusal is primarily driven by specific technical concerns regarding mRNA safety and institutional mistrust rather than general anti-vaccination ideology, suggesting that transparent communication addressing these specific fears may be more effective than enforcement.
This study demonstrates that violet light induces apoptosis in chordoma cells by increasing reactive oxygen species levels and triggering mitochondrial damage, suggesting a promising new therapeutic approach for this radiotherapy-resistant tumor.
This feasibility study evaluated the usability and trust of a virtual reality AVATAR therapy interface across three groups, finding that while the system is generally user-friendly, individuals experiencing auditory verbal hallucinations perceive the avatar creation and interaction process as significantly more challenging than control and healthy participants.
This observational study demonstrates that a hybrid simulation training program, combining educational videos, role-playing with actors, and multidisciplinary debriefing, significantly reduced healthcare professionals' anxiety levels regarding parental presence during critical NICU events, though the findings are limited by the lack of a control group.