📄 medicine

Association Between Early Plasma Transfusion Burden and Mortality and Infection-Associated Organ Dysfunction in Severe Trauma Patients: A Single-Center Retrospective Exploratory Study

This single-center retrospective exploratory study of 100 severe trauma patients suggests a preliminary association between early 24-hour plasma transfusion volume and increased 30-day mortality risk, while finding no significant link between transfusion burden or injury severity and early infection-associated organ dysfunction, though the small sample size necessitates validation in larger prospective trials.

Ziyun Li, Junyan Wang, Zhoubo Wang, Yuechuan Shen2026-10-19
📄 medicine

Thenar Muscle Thickness Assessed by Point-of-Care Ultrasound and Geriatric Vulnerability in Hospitalized Older Adults: A Pilot Study

This pilot study of 50 hospitalized adults aged 75 and older found that greater thenar muscle thickness, measured via point-of-care ultrasound, is significantly associated with better nutritional status and lower risks of pressure injuries and falls, suggesting its potential utility as a pragmatic marker for geriatric vulnerability despite the study's small sample size and lack of a sarcopenia reference standard.

Nelson Anzoletti, Michela Giansante, Claudia Paolini, Lucia Fasciani, Andrea Boccatonda, Alessia Di Lorito, Giulio Cocco (…)2026-10-19
📄 medicine

When tiny lungs Struggle to breathe; a rare cause of Refractory Primary Pulmonary Hypertension

This paper presents a fatal case of a 2-day-old infant with refractory primary pulmonary hypertension, ultimately diagnosed post-mortem as Alveolar Capillary Dysplasia with Malpositioned Pulmonary Veins (ACD/MPV), highlighting the critical need for clinical suspicion and thoracic pathology expertise to identify this rare and lethal congenital disorder.

Monica Sivakumar, Donna C Philip, Maria Frances Bukelo2026-10-19
📄 medicine

Prenatal Education Needs and Preferences by Educational Attainment Among Pregnant Patients: A Prospective, Cross-sectional Observational Study

This prospective cross-sectional study reveals that while pregnant patients across all educational backgrounds share a similar high interest in prenatal education, those with lower educational attainment prioritize different informational topics—specifically normal pregnancy changes and labor induction—highlighting the need to individualize counseling content based on educational level.

Zoe Keese, Rebecca Anderson, Rachel Weber, Heather Ramsey, Mridula Ghotane, Santiago Ortiz Barragan, Rebecca Rimsza2026-10-19
📄 medicine

Primary Extramedullary Plasmacytoma of the Ileum: A Rare Diagnostic Challenge with Clinicopathological Correlation and Review of the Literature

This paper presents a rare case of primary extramedullary plasmacytoma in the ileum of a 40-year-old patient, highlighting the diagnostic challenges posed by its non-specific symptoms and imaging features, and emphasizing the necessity of histopathological confirmation with immunohistochemistry and systemic workup to differentiate it from other neoplasms and rule out multiple myeloma.

Anurag Singh, Akansha Singh, Akansha Rastogi, Prachi Chaudhary, Rahul Rahul, Surya Kant, Pallavi Prasad2026-10-19
📄 medicine

First-line treatment of non-haemorrhagic early miscarriage in gynaecological emergencies in public hospitals on Reunion Island in 2022

A 2022 cross-sectional study of public hospitals in Reunion Island found that non-surgical management (primarily expectant or pharmacological) was the preferred first-line treatment for the vast majority of patients with non-haemorrhagic early miscarriage, suggesting a need to expand out-of-hospital care networks.

Pierric GIROU, Marion LAVILLE, Laura MATARD, Laurie SAVARY, Sébastien LERUSTE, Éric BERTRAND, Jessica DUMEZ2026-10-19
📄 medicine

Effectiveness of a Structured Educational Module on Knowledge, Attitude and Acceptability Related to Wet Nursing among Postnatal Mothers at a Selected Hospital, Greater Noida, and Uttar Pradesh: A Quasi-Experimental Study

This quasi-experimental study demonstrates that a structured educational module significantly improved knowledge, attitude, and acceptability regarding wet nursing among postnatal mothers in Greater Noida, India, compared to routine care.

Sonalika Shah¹, Rekha Kumari, Sabita Thapa Magar, Sandhya Kumari, Jyoti Patel2026-10-19
📄 medicine

Association of renal impairment gradient with coronary plaque burden assessed by intravascular ultrasound in patients with type 2 diabetes: a single-center retrospective study

This single-center retrospective study of 129 patients with type 2 diabetes found that increasing renal impairment is associated with higher coronary plaque burden on intravascular ultrasound, an association that remains significant after adjusting for conventional cardiometabolic risks but is substantially attenuated when accounting for phosphorus, inflammatory, and nutritional markers.

Ying Yan, Qin Shen, Wenyao Li, Tielong Chen2026-10-19