13699 papers
This study provides preliminary psychometric evidence that the 10-item clinician-rated NMSS-OFF/ON scale is a valid, internally consistent, and highly responsive instrument for assessing non-motor fluctuations in Parkinson's disease, though larger independent studies are needed to fully establish its structural validity and clinical thresholds.
While health profession students and disaster response organizations in Germany both express high willingness to integrate students into emergency surge capacity, their specific task expectations diverge significantly, with students favoring patient-facing acute care and organizations prioritizing logistical and nursing support, highlighting a critical need to align these perspectives through targeted training and insurance frameworks.
A five-day community-based immersion program significantly improved second-year medical students' attitudes toward people with disabilities, reduced their discomfort, and enhanced their perceived social competence and coping skills, highlighting the value of direct interaction in medical education while suggesting the need for broader, longitudinal curriculum integration.
In a prospective multicenter single-arm trial involving 97 patients, the novel LeesCa™ balloon angiographic catheter demonstrated 100% device success and a 98.97% procedural success rate with a low adverse event profile, confirming its safety and efficacy for coronary venography during left ventricular lead implantation for cardiac resynchronization therapy.
This retrospective cohort study of the US National Trauma Database (2017–2020) reveals that while nonoperative management is the predominant approach for pediatric pancreatic trauma, operative management is associated with significantly longer hospital and ICU stays but lower mortality rates, supporting the need for individualized treatment strategies.
A high-throughput screen identified the proteasome inhibitor ixazomib citrate as a promising therapeutic strategy that selectively targets and inhibits the growth of ALK-mutant neuroblastoma tumors both in vitro and in vivo.
This case report illustrates that secondary syphilitic hepatitis can mimic autoimmune liver disease through overlapping cholestatic biochemistry and positive autoantibodies, highlighting the critical importance of syphilis testing to avoid inappropriate immunosuppression and ensure resolution with antimicrobial therapy.
This prospective observational study of 40 breath-hold divers demonstrates that prolonged dry static apnea induces a significant, rapid-onset increase in intraocular pressure that correlates with elevated blood pressure and decreased oxygen saturation, likely driven by increased episcleral venous pressure, followed by immediate normalization upon resumption of breathing.
In patients with acute coronary syndrome, admission Tpeak–Tend interval and Tp-e/QTc ratio correlate with angiographic and clinical severity, with the Tp-e/QTc ratio serving as an independent predictor of six-month adverse outcomes that enhances the prognostic accuracy of the GRACE score.
While AI-generated feedback for informed consent training was rated as higher quality and more comprehensive than surgeon-generated feedback, the AI systematically assigned more favorable performance scores, indicating that high feedback quality does not guarantee evaluative validity and highlighting the need for human oversight in nuanced surgical assessments.