📄 medicine

Evaluation of Blood Glucose Levels in Patients having Chemotherapy Treatment in Combination with Corticosteroids: A Prospective Cohort Study

This prospective cohort study of 148 patients undergoing chemotherapy with corticosteroids found that steroid-induced hyperglycemia is common, particularly in those with pre-existing diabetes, and that 12% of non-diabetic patients developed steroid-induced diabetes by week 12, highlighting the need for universal nurse-led blood glucose monitoring and management.

Shona Vigus, Alexis Cranfield, Stephen James Edmondston, Kynan Feeney2026-10-19
📄 medicine

Observability of Fifth Universal Definition of Myocardial Infarction components in linked electronic health records: a retrospective MIMIC-IV study

This retrospective MIMIC-IV study demonstrates that while linked electronic health records can partially operationalize components of the Fifth Universal Definition of Myocardial Infarction, significant gaps in data availability—particularly regarding ECG reports, imaging, and adjudication—limit the feasibility of fully retrospective evaluation without local prospective verification.

Hongwei Tan, Zheng Liu, Zhixin Li, Yucheng Xie, Zhuo Chen, Yongmei Nie, Fengxu Yu2026-10-19
📄 medicine

Extraction Decision and Tooth Selection in Borderline Orthodontic Cases: A Cross- Sectional Survey of Orthodontists

This cross-sectional survey of 138 orthodontists reveals that while localized intraoral characteristics in borderline cases significantly influence which premolar is selected for extraction, the overall decision to extract remains relatively stable and is more strongly associated with the clinician's preference for fixed buccal appliances versus clear aligners.

Ezgi Cansu Firinciogullari, Kaan Keskin, Aslıhan Mediha Erdinc, Sercan Akyalcin2026-10-19
📄 medicine

Questionnaire survey on healthcare providers’ awareness of PGT-M and their perceptions of the preference of individuals diagnosed with cancer predisposition syndromes: A single-center study in  Japan

This single-center study in Japan reveals that while over 90% of oncology healthcare providers recognize patient interest in reproductive options for cancer predisposition syndromes, only 20% are actually aware of Preimplantation Genetic Testing for Monogenic Disorders (PGT-M), highlighting an urgent need for improved provider education and support systems.

Hiromi Arakawa, Keika Ksneko, Eri Habano, Yuko Minoura, Asami Kuga, Akito Dobashi, Kota Ishioka, Arisa Ueki2026-10-19
📄 medicine

Age-related Changes in the Morphological Types of Ankyloglossia in Infants with Feeding Problems

This study of 404 infants with feeding problems reveals that the morphological subtypes of ankyloglossia shift significantly with age—specifically, a decrease in anterior membrane types and an increase in tower types—suggesting structural remodeling rather than simple elongation and indicating that delaying surgical intervention in anticipation of spontaneous improvement may be inappropriate.

Yasuo Ito2026-10-19
📄 medicine

Metric-dependent evaluation of a retrieval-augmented large language model workflow for oral squamous cell carcinoma treatment planning: a retrospective study

This retrospective study demonstrates that the ranking of four RAG-enabled LLMs for oral squamous cell carcinoma treatment planning varies significantly depending on the evaluation metric used, highlighting the limitations of relying on single aggregate scores to determine clinical model performance.

Min Wu, Xiaozhe Li, Xindi Wei, Huiyong Zhu2026-10-19
📄 medicine

Moral Distress and Associated Factors Among Nurses Working at Government Hospitals in Dessie City Administration, Northeast Ethiopia

This 2024 cross-sectional study of 355 nurses in Dessie City, Ethiopia, found a high prevalence (66.5%) of moral distress significantly associated with factors such as perceived powerlessness, lack of confidence in decision-making, inadequate staffing, weak organizational support, and job dissatisfaction.

Jemal Mohammed Bahru, Honelet Debebe Dagne, Mohammed Mechal Adem2026-10-19
📄 medicine

Mefloquine Prophylaxis Results and Evaluation of adVerse Effects iN Peacekeepers Travelling to South Sudan: Mefloquine PREVENT–SS Study

This retrospective study of Indian UN peacekeepers in South Sudan demonstrates that consistent adherence to Mefloquine prophylaxis significantly reduces malaria risk, though fear of and experience with neuropsychiatric adverse effects remain the primary barriers to compliance.

Abhinav Kumar, Dheeraj Uppaluri, Deepak Sharma, Ankita Patel, Amit Sharma, P. Basavaraj2026-10-19
📄 medicine

Ethical tensions experienced by healthcare professionals in supportive cancer care: a qualitative study proposing a classification

This qualitative study identifies and classifies ethical tensions experienced by healthcare professionals in supportive cancer care into non-dilemmatic and dilemmatic categories, proposing the PTR (Patient, Temporality, Resources) model as a diagnostic tool to address the recurrent causes of these tensions and improve access to care.

Soumya Anane-Abrous, Philippe Tessier, Guillaume Durand, Isabelle Cojean-Zelek2026-10-19
📄 medicine

Identical results, hidden data problems: running CMS's digital quality measures on real hospital data

This study demonstrates that while CMS's digital quality measures for severe hypoglycemia and hyperglycemia can be executed efficiently and consistently on real hospital data using FHIR, the resulting metrics are highly sensitive to underlying data quality issues—such as missing units and admission status classifications—rather than execution engine errors, underscoring the critical need for data readiness testing before mandatory FHIR reporting.

Sai Sharan Kasa2026-10-19