3359 papers
This study demonstrates that distinct angiographic patterns of supraclinoid internal carotid artery blister-like aneurysms correlate with varying degrees of lesion instability and natural history, supporting the need for individualized surveillance and treatment strategies.
This randomized controlled trial in Brazil demonstrates that a telephone-based brief intervention delivered by nurses effectively reduces risky alcohol use among women in primary care for up to six months, though the benefits may diminish over time without booster sessions.
This cross-sectional study of 107 transfusion-dependent thalassaemia patients reveals a high prevalence of iron overload and endocrine abnormalities, particularly delayed puberty and altered LH and testosterone levels, though no statistically significant association was found between these hormonal disturbances and serum ferritin levels or iron chelation therapy adherence.
This multicenter study establishes sex- and age-specific reference ranges for CT-derived airway parameters in older Chinese adults with normal lungs, revealing that airway structure is primarily determined by sex, body size, and smoking status rather than age, thereby challenging the conventional assumption of progressive age-related airway thickening.
This study utilizes single-cell RNA sequencing and a computational framework to reveal that hypoxia-induced senescence in nasopharyngeal carcinoma drives immunosuppression via the MIF-CD74 axis, leading to the identification of a novel prognostic transcription factor signature and actionable therapeutic targets.
This study challenges the "healthy migrant effect" by demonstrating that foreign-born U.S. adults have a higher burden of undiagnosed diabetes compared to native-born adults, suggesting that apparent health advantages stem from lower rates of clinical detection due to barriers in healthcare access rather than a genuinely lower disease prevalence.
This study demonstrates that integrating functional lung imaging features ("Functionomics") with conventional radiomics and dosiomics significantly enhances the predictive accuracy for grade ≥2 radiation pneumonitis in lung cancer patients compared to using anatomical or dosimetric data alone.
This retrospective cohort study of 216 patients demonstrates that delaying definitive surgical treatment for maxillofacial fractures beyond 72 hours significantly increases the risk of postoperative infections and overall complications, particularly for mandibular fractures, compared to early intervention.
This study demonstrates that short-term carbohydrate restriction in newly diagnosed acute myeloid leukemia patients reprograms leukemic metabolism by suppressing anabolic processes in proliferative blasts while revealing hierarchical metabolic vulnerabilities in therapy-persistent stem-like populations, thereby establishing organism-level dietary intervention as a therapeutic framework for targeting leukemia.
This randomized controlled trial demonstrates that using a low CO₂ insufflation rate of 1 L/min, compared to the standard 5 L/min, significantly better preserves cardiac output and stroke volume while reducing systemic vascular resistance during gynecological laparoscopic surgery without compromising surgical efficiency.