🦠 Category

microbiology

771 papers

Microbiology explores the invisible world of tiny life forms that shape our health, environment, and even the air we breathe. From bacteria and viruses to fungi and parasites, this field investigates how these microscopic organisms interact with us and each other, driving everything from disease outbreaks to beneficial fermentation processes. Understanding them is crucial for developing new medicines, improving food safety, and combating global health challenges.

At Gist.Science, we make the latest discoveries in this dynamic field accessible to everyone. We process every new preprint uploaded to bioRxiv in this category, transforming dense academic findings into both clear, plain-language explanations and detailed technical summaries. This ensures that whether you are a student, a researcher, or simply curious, you can grasp the significance of cutting-edge science without getting lost in jargon.

Below are the most recent papers in microbiology, curated and summarized directly from the bioRxiv server to keep you at the forefront of discovery.

🦠 microbiology

Culture-Free Rapid Phenotypic Antimicrobial Susceptibility Testing for Helicobacter pylori Based on Fluorescence Rapid On-Site Evaluation Technology: A Preliminary Study

This preliminary study introduces and validates a novel, culture-free fluorescence-based rapid on-site evaluation (ROSE) method that delivers phenotypic antimicrobial susceptibility testing for *Helicobacter pylori* within one hour, offering a same-day alternative to traditional 5–7 day culture methods and successfully assessing amoxicillin susceptibility where genotypic tests fail.

Li, B., Zhang, L., Hou, Y., Wu, K., Han, J., Liu, J., Zhang, J., Yang, M.2026-07-06
🦠 microbiology

Enhanced inter-chain hydrogen bonding in the murine norovirus VP1 capsid leads to increased particle stability and delayed viral uncoating

This study demonstrates that introducing specific amino acid substitutions in the murine norovirus VP1 capsid protein enhances inter-chain hydrogen bonding, resulting in a virus with increased thermal and pH stability and delayed uncoating, which offers valuable insights for designing thermostable norovirus vaccines.

Mills, J. T., Lewis, C. B., Sherry, L., Farnell, J., Rowlands, D., Hosie, M. J., Bhella, D., Herod, M. R.2026-07-05
🦠 microbiology

Bacillus adaptation to Pseudomonas secondary metabolites enhances its root competitiveness

This study demonstrates that prolonged exposure to secondary metabolites from the competing rhizobacterium *Pseudomonas sessilinigenes* drives rapid adaptive evolution in *Bacillus velezensis*, resulting in a subpopulation with enhanced root colonization and competitive fitness in the plant microbiome.

Balleux, G., Zarattini, M., Anckaert, A., Van Buren, L., Ribeiro Monteiro, S., Rigali, S., Ongena, M.2026-07-05
🦠 microbiology

Performance of pathogen identification and resistance gene expression tests using ASTar(R) remnant bacterial suspension in Gram-negative contrived positive blood cultures

This study demonstrates that using remnant bacterial suspensions from the ASTar system for MALDI-TOF MS identification and lateral flow assay-based resistance detection in Gram-negative blood cultures provides rapid, accurate results with high confidence and potential cost savings compared to commercial multiplex PCR.

Gupta, V., Myers, M., Niklasson, I., Vincentsson, S., Ring, E., Mainwaring, O., Brown, N., Grawe, J.2026-07-04
🦠 microbiology

Phycosphere-associated bacteria differentially impact accessibility of dust-bound iron to model diatom Phaeodactylum tricornutum

This study demonstrates that specific phycosphere-associated bacteria, such as *Marinobacter*, can significantly enhance the growth of the model diatom *Phaeodactylum tricornutum* under iron-limited conditions by facilitating the solubilization and uptake of dust-bound iron, whereas other strains like *Stappia* may suppress this growth.

Coffey, N. R., Newell, B. N., Manning, K., Rolison, K. A., Mayali, X., Stuart, R. K., Boiteau, R. M.2026-07-01
🦠 microbiology

Environmental Drivers and Distribution of Pathogenic Vibrio Species in the Teign Estuary, UK

This study reveals that rising sea surface temperatures and sewage pollution in the Teign Estuary, UK, are fostering a diverse, virulent, and multidrug-resistant community of pathogenic *Vibrio* species, including newly identified strains, thereby posing significant risks to both public health and aquaculture.

Boote, H., Coyle, N. M., Forde, A., Alexa, I., Burchell, M., Reynolds, S., Studholme, D. J., Wagley, S.2026-07-01
🦠 microbiology

Adaptation of Methylobacterium extorquens to alternating carbon sources identifies the regulator CstR as an intersectional hub of cellular carbon metabolic dynamics and stress response

This study identifies the orphan response regulator CstR in *Methylobacterium extorquens* as a critical hub that coordinates cellular responses to carbon source transitions and stress, where its loss-of-function mutations enhance metabolic flexibility between methanol and succinate while revealing a complex trade-off between growth optimization and resilience to specific environmental stressors.

Bruger, E. L., Ikobe, I., Hellenbrand, C. N., Zigmund, U., Bazurto, J. L.2026-07-01
🦠 microbiology

Effect of CSFV on Differential Genes of Histone Lactylation at H3K18 in the PI3K-AKT Signaling Pathway

This study demonstrates that Classical swine fever virus (CSFV) infection significantly alters histone lactylation at the H3K18 site in 3D4/21 cells, leading to the differential regulation of specific genes within the PI3K-AKT signaling pathway, including the upregulation of THBS4, thereby providing new insights into the molecular mechanisms of viral replication and immune evasion.

Zhang, H., Han, Z., Zhao, X., Zhu, J., Shao, N., Sun, K., Li, W., Yao, Y., Liang, X., Yang, M., Gao, Y., Chen, J., Liang (…)2026-06-29