653 papers
Microbiology explores the invisible world of tiny life forms that shape our health, environment, and even the air we breathe. From bacteria and viruses to fungi and parasites, this field investigates how these microscopic organisms interact with us and each other, driving everything from disease outbreaks to beneficial fermentation processes. Understanding them is crucial for developing new medicines, improving food safety, and combating global health challenges.
At Gist.Science, we make the latest discoveries in this dynamic field accessible to everyone. We process every new preprint uploaded to bioRxiv in this category, transforming dense academic findings into both clear, plain-language explanations and detailed technical summaries. This ensures that whether you are a student, a researcher, or simply curious, you can grasp the significance of cutting-edge science without getting lost in jargon.
Below are the most recent papers in microbiology, curated and summarized directly from the bioRxiv server to keep you at the forefront of discovery.
This study demonstrates that the snake-associated Swiss snake colony virus 1 (SwSCV-1), a member of the *Kolmioviridae* family, encodes only a single form of the delta antigen and does not translate its additional open reading frame 2, distinguishing its protein expression profile from that of the hepatitis D virus.
This study reveals that carbapenem resistance in a Nigerian ICU is driven by the horizontal spread of a conserved mobile resistance island carrying *bla*NDM-5 across diverse *Enterobacter hormaechei* and *Klebsiella pneumoniae* strains, highlighting the critical need to track mobile genetic elements alongside bacterial lineages for effective infection control in low-resource settings.
This study demonstrates that the virtual colony count assay reveals a pronounced inoculum effect of the antimicrobial peptide HNP1 against *Staphylococcus aureus* ATCC 29213, which is associated with biofilm formation as a resistance mechanism.
This study compared antibiotic resistance genes, virulence factors, and pathogen profiles across households in Mysuru, Dubai, and Tucson, revealing significant geographic variations in resistance and viral diversity while identifying a core set of resistance genes present in all locations.
This study demonstrates that extracellular vesicles secreted by a polymicrobial community of CF lung pathogens exacerbate innate immune responses and inhibit CFTR function in cystic fibrosis epithelial cells, explaining why highly effective modulator therapies like Trikafta fail to eliminate chronic infections or restore normal lung physiology.
The paper introduces PALM, a fast and reliable quasi-Poisson regression framework designed to improve false discovery control, statistical power, and computational efficiency in large-scale microbiome association studies and meta-analyses.
This study confirms that *Pleurotus ostreatus* cultivated on Nigerian agro-waste substrates (Gmelina sawdust, oil palm fiber, and cassava peels) yields bioactive extracts with significant antifungal and antioxidant properties, demonstrating that substrate choice substantially influences the mushroom's therapeutic potential.
This study demonstrates that the IL-1 family is essential for initiating mucosal immunity against *Candida albicans* by regulating antimicrobial peptides and neutrophil responses, thereby preventing local infection from progressing to fatal systemic dissemination, particularly in neutropenic patients.
The paper introduces LGTM, a probabilistic framework that integrates Gaussian processes with neural topic modeling to simultaneously discover interpretable microbial subcommunities and model their complex longitudinal dynamics in response to host and environmental covariates.
This study demonstrates that specialized legume-based culture media derived from soybean and pea tissues effectively overcome the challenge of unstable sporulation in soybean-associated *Cercospora* species, offering a more reliable and robust alternative to standard artificial media for laboratory research.