📄 Category

nephrology

15 papers

Nephrology focuses on understanding and treating the kidneys, the vital organs responsible for filtering waste from our blood and balancing fluids in the body. This dynamic field tackles everything from common issues like kidney stones and infections to complex chronic diseases that require lifelong management. As researchers push the boundaries of what we know about renal health, new discoveries emerge daily, offering hope for better treatments and prevention strategies.

At Gist.Science, we ensure these advancements reach everyone by curating the latest preprints directly from medRxiv. Our team processes every new submission in this category, transforming dense scientific findings into clear, plain-language summaries alongside detailed technical analyses. This dual approach allows both curious readers and medical professionals to stay informed without getting lost in complex jargon.

Below you will find the most recent preprints covering the latest breakthroughs and studies in kidney health and disease.

Cross-sectional Surveys: Impact of Kidney-CAP availability on health provider and patient decisions related to vascular access, dialysis modality and kidney transplantation

This cross-sectional survey study demonstrates that the availability of the Kidney-CAP bleeding cessation device positively influences clinical decision-making by increasing patients' desire for arteriovenous fistula creation and kidney transplantation, while prompting healthcare providers to recommend home hemodialysis more frequently.

Forster, A., Rehman, F., Moist, L., Holden, R., Thomson, B. K.2026-03-10📄 nephrology

Shared multicellular injury programs of acute and chronic kidney disease enable mechanistic patient stratification

This study utilizes single-nucleus transcriptomics of over 150 kidney biopsies to identify shared multicellular injury programs in acute and chronic kidney disease that transcend traditional clinical categories, revealing non-invasive protein signatures predictive of long-term renal outcomes.

Fallegger, R., Gomez-Ochoa, S. A., Boys, C., Ramirez Flores, R. O., Tanevski, J., Pashos, E., Feliers, D., Piper, M., Schaub, J. A., Zhou, Z., Mao, W., Chen, X., Sealfon, R. S. G., Menon, R., Nair, V. (…)2026-03-06📄 nephrology

Agreement between cystatin-C and creatinine based estimated glomerular filtration rate among Ethiopian children.

This study of 350 Ethiopian children found poor agreement between cystatin C- and creatinine-based estimated glomerular filtration rates, revealing that creatinine-based equations significantly overestimate kidney function compared to cystatin C-based estimates, thus highlighting the need for local validation using gold-standard clearance methods.

Tefera, B., Ali, R., Megersa, B. S., Girma, T., Friis, H., Abera, M., Belachew, T., Olsen, M. F., Filteau, S., Wells, J. C., Wibaek, R., Yilma, D., Nitsch, D.2026-03-06📄 nephrology

Serum Total Immunoglobulin-E Levels and Early Loss of eGFR in Individuals at Risk of Mesoamerican Nephropathy: A Nested Case-Control Analysis from a Population Representative Follow-Up Study

This nested case-control study identifies that elevated serum total immunoglobulin E (IgE) levels precede the early loss of kidney function in individuals at risk of Mesoamerican Nephropathy, suggesting that IgE-mediated pathways, potentially driven by infections or allergies rather than heat exposure, may play a central role in the disease's etiology.

Caplin, B., Agarwal, S., Day, A., Al-Rashed, A., Oomatia, A., Gonzalez-Quiroz, M., Pearce, N.2026-03-02📄 nephrology

Defining the Global Landscape of Kidney Genetics Care-A Scoping Review and International Stakeholder Consultation of Clinic Models and Outcomes

This scoping review and international stakeholder consultation characterize the global landscape of kidney genetics care, identifying four distinct clinic models and regional variations in funding and testing strategies while emphasizing that effective implementation and diagnostic success depend more on patient selection and support structures than on the specific testing modality used.

Lim, R. S., Harris, T., Jefferis, J., Jahan, S., Lim, R. S., D Arrietta, L. M., Ng, K. H., Chin, H. L., Goh, L. L., Acharyya, S., Chan, E. C. Y., Patel, C., Biros, E., Sevdalis, N., Mallett, A. J.2026-02-15📄 nephrology