228 papers
Neurology explores the intricate workings of the brain and nervous system, tackling everything from memory and movement to complex conditions like epilepsy and Alzheimer's. This field seeks to understand how our minds function and what happens when that delicate machinery falters, aiming to improve lives through better diagnosis and treatment.
At Gist.Science, we make the latest research from medRxiv accessible to everyone. We process every new preprint in this category, offering both straightforward plain-language explanations and detailed technical summaries so you can grasp the science at your own pace. Below are the latest papers in neurology, ready for you to explore.
This cross-sectional study of 4,060 Parkinson's disease patients at a tertiary center reveals that 22% are eligible for neuromodulation and that the procedure offers significant clinical benefits alongside an estimated annual cost saving of R$ 8,247 per patient.
This systematic review and meta-analysis of nearly one million adult traumatic brain injury patients reveals that females have lower mortality than males, while explainable machine learning identifies mean age, study sex composition, and study quality as key factors contributing to the heterogeneity in reported sex-specific mortality effects.
This study demonstrates that while plasma neurofilament light (NfL) is the strongest single biomarker for distinguishing frontotemporal lobar degeneration (FTLD) from controls, a multiplex proteomic approach combining CNS-related and inflammatory signatures provides complementary insights into syndrome heterogeneity, regional brain atrophy, and patient survival.
Intimate partner violence involving brain injuries can cognitively age female survivors by over a decade, resulting in severe, under-recognized deficits in memory and reaction time that may hinder their ability to escape further abuse.
This study demonstrates that speech timing measures are not interchangeable across different elicitation methods for cognitive monitoring in senior living residents, as their correspondence varies significantly based on the shared retrieval demands of tasks like category fluency, picture description, and narrative generation.
This study demonstrates that two automated acoustic measures, Nasal Cognate Distinctiveness (NCD) and nasal posterior probability (NPP), serve as reliable, objective markers for assessing hypernasality severity in motor speech disorders, with NPP uniquely capturing relevant acoustic information across both consonants and vowels.
The Study of Ancestry, Health, Environment, and Late-Life Neurodegeneration (SAHEL) establishes a comprehensive research platform in north-eastern Nigeria that integrates diverse clinical, environmental, genomic, and imaging data from over 1,000 older adults to investigate population-specific mechanisms of cognitive decline and advance dementia research in sub-Saharan Africa.
This study integrates multiparametric 7 Tesla MRI and intracranial electrophysiology to reveal altered thalamic sodium homeostasis and structural changes in drug-resistant focal epilepsy, establishing a multimodal framework for characterizing pathological network nodes to support patient stratification and personalized therapeutic strategies.
This multimodal study reveals that reduced glucose metabolism in the posterior medial cortex of patients with disorders of consciousness is linked to impaired mitochondrial energy production and a shift toward synaptic inhibition, while baseline choline levels serve as a predictor for long-term clinical recovery.
This study demonstrates that elevated myo-inositol levels in the right inferior frontal gyrus, measured via 7 Tesla MRS, serve as a promising non-invasive biomarker for neuroinflammation in frontotemporal lobar degeneration, correlating significantly with both peripheral inflammatory markers and cognitive decline.