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958 papers

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Adiposity, Skeletal Muscle Mass and Handgrip Strength in Relation to Hepatic Steatosis and Liver Fibrosis in Individuals with Type 2 Diabetes Mellitus: A Dual-Energy X-ray Absorptiometry and Transient Elastography Study

In adults with type 2 diabetes, greater total and visceral adiposity is strongly associated with hepatic steatosis and fibrosis, while advancing fibrosis risk is characterized by a dissociation where muscle mass increases with obesity but muscle function declines, highlighting the need to assess both adiposity and muscle function for liver risk stratification.

Surender ., Pushpender Khatana, Sunil Kumar Mishra, Mohammad Shafi Kuchay, Rajesh Rajput2026-07-27
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A Novel Mobile Health Software Platform to Improve Emergency Medical Systems: 912Rwanda

This paper presents the development, implementation, and evaluation of 912Rwanda, a highly reliable and usable mobile health software platform that successfully integrated emergency communication systems in Rwanda, offering a scalable model for improving emergency medical services in low- and middle-income countries.

Teresa M Bell, Jean Marie Uwitonze, Jeanne d'Arc Nyinawankusi, Rebecca Maine, Andrea Nicole Davis, Jean Habanabakize, Me (…)2026-07-27
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Group Performance of Geosynthetic-Encased Stone Columns for Embankment Applications on Soft Clay: A Numerical Study

This numerical study demonstrates that geosynthetic-encased stone columns (GESCs) significantly enhance the bearing capacity and settlement performance of embankments on soft clay, with optimal results achieved through high-stiffness encasements, full-length installation, and group configurations that accelerate pore water pressure dissipation.

Pooja Bhatia, Murtaza Hasan, Shahbaz Ahmad, Abdullah H Alsabhan, Jibran Qadri, Shamshad Alam2026-07-27
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Characterization of urinary microbiome dysbiosis in prostate cancer and benign prostatic hyperplasia: A metagenomics study from North-Eastern Algeria

This metagenomics study from North-Eastern Algeria characterizes distinct urinary microbiome dysbiosis in prostate cancer and benign prostatic hyperplasia patients compared to controls, identifying specific microbial signatures and demonstrating how chemotherapy further disrupts this ecosystem, thereby suggesting the urinary microbiome as a promising non-invasive biomarker and therapeutic target for prostate diseases.

Amel Amel Abderahim, Florian Salipante, Nassima Djahmi, Mohamed Lahlou Redjdal, Malik Atoui, Karim Atoui, El Mahdi Bacco (…)2026-07-27
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Ex Vitro Physiological, Antioxidant and Metabolomic Responses of Salt-Tolerant Salicornia lagascae Clones Derived from Solid and Liquid Micropropagation Systems

This study demonstrates that *Salicornia lagascae* clones derived from liquid micropropagation systems exhibit superior physiological and metabolic acclimation to high salinity compared to solid-system clones, highlighting in vitro selection as an effective strategy for generating elite halophytic germplasm for saline agriculture and soil restoration.

Ghofrane Atrous, Pedro Diaz-Vivancos, Abel Piqueras, Ana Hernández-Cánovas, Gregorio Barba-Espin, José Antonio Hernández2026-07-27
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Educational inequalities in cognitive-functional transitions among adults aged 65 years and older in China and the United States: parallel longitudinal analyses of CHARLS and HRS

This study utilizes parallel longitudinal analyses of the CHARLS and HRS cohorts to demonstrate that lower education consistently predicts a higher risk of transitioning to low cognitive performance among adults aged 65 and older in both China and the United States, whereas associations with functional (ADL) transitions are smaller and less consistent after adjustment.

Shikun Li, Xu Chen, Rudong Chen, Zhuo Yang, Yuyang Hou, Jiasheng Yu2026-07-27
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Cell-resolved cortical architecture and intercellular communication distinguish bipolar and major depressive disorders

This study utilizes a large-scale, harmonized single-nucleus transcriptomic resource of the dorsolateral prefrontal cortex to demonstrate that while Major Depressive Disorder involves broad transcriptomic dysregulation and vascular-associated glial alterations, Bipolar Disorder is characterized by a distinct oligodendroglial signature and attenuated neuronal communication, revealing divergent cellular architectures that could inform future biological stratification of mood disorders.

Laura Orsolini, Matteo Giulietti, Giulio Longo, Francesco Piva, Umberto Volpe2026-07-27
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Divergent hepatitis B neutralizing antibody trajectories after spontaneous control in people with and without HIV

This study reveals that while spontaneous control of hepatitis B leads to increasing functional neutralizing antibodies in people without HIV, those with HIV fail to maintain these protective antibody levels, likely due to persistent antigen production that impairs immune recovery and heightens reactivation risk.

Chloe Thio, Che-Min Lo, Eric Seaberg, Mark Anderson, Maraake Taddese, Jessica Mimms, Ernesto Marques, Mallory Witt, Stev (…)2026-07-27