❤️ Category

physiology

76 papers

Physiology explores how living systems function, from the microscopic signals inside a single cell to the complex rhythms of an entire organism. This field seeks to understand the mechanical, physical, and biochemical processes that keep life moving, offering crucial insights into health, disease, and the body's remarkable ability to adapt.

On Gist.Science, we process every new preprint in this category from bioRxiv to make these rapid discoveries accessible to everyone. For each study, we provide both a clear, plain-language explanation and a detailed technical summary, ensuring that whether you are a curious student or a seasoned researcher, you can grasp the latest findings without getting lost in jargon.

The papers listed below represent the newest physiological research recently shared on bioRxiv, ready for you to explore.

Five days of heat acclimation improves cardiovascular and thermoregulatory responses without altering renal stress biomarkers in endurance athletes

Five days of isothermic heat acclimation enhances cardiovascular and thermoregulatory performance in endurance athletes by lowering resting heart rate, expanding plasma volume, and increasing sweat loss, yet it fails to mitigate renal tubular stress, fluid-regulatory strain, or sympathetic activity during subsequent exercise in hot, humid conditions.

Snape, D., Wainwright, B., Parsons, I. T., Stacey, M. J., Woods, D. R., OHara, J.2026-03-09❤️ physiology

Seasonal Dynamics of Nonstructural Carbon Compounds in Pine Forest

This study reveals that in temperate pine forests, seasonal carbon balance is primarily driven by the rapid redistribution of soluble sugars rather than significant fluctuations in overall non-structural carbon storage, as evidenced by year-round measurements showing sugars account for the majority of annual flux while starch and lipids play more stable or secondary roles.

Sarpong, C. K., Nkrumah, M. K., Baniya, B., Kim, D., Noormets, A.2026-03-08❤️ physiology

Circadian phase and sex shape swimming exercise responses and stereotyped behaviors in mice

This study demonstrates that circadian phase and sex interact to differentially modulate swimming behaviors, physiological stress responses, and post-exercise emotional outcomes in mice, highlighting the critical need to account for these factors in preclinical exercise research.

Cortes Soto, M. D., Wang, C., Kang, E., Martinez, S., Toller, J. M., Vasquez, H. E., Herrera, S. V., Alvina, K.2026-03-06❤️ physiology

MATR3 is essential for oocyte growth and maturation quality through a dual molecular mechanism

This study demonstrates that the RNA-binding protein MATR3 is essential for oocyte growth and maturation quality by orchestrating transcription and paracrine signaling through a dual mechanism involving H3K9me2 demethylation and direct promoter binding, with its dysfunction leading to infertility and human oocyte maturation arrest.

Bao, Y., Zuo, Z., Wang, T., Lin, L., Gao, M., Qin, S., Yang, Q., Liu, B., Sun, W., Ma, J., Zhu, T., Xia, G., Zhou, B., Hu, R., Zhang, H., Wang, F., Wang, C.2026-03-03❤️ physiology

Improved Classification of Acute Physical Fatigue Using Salivary Proteomic Biomarkers: An Exploratory Study

This exploratory study demonstrates that an untargeted salivary proteomic panel outperforms targeted stress-related molecules in accurately classifying acute physical fatigue, suggesting a promising non-invasive approach for monitoring operational readiness in tactical athletes.

Lindsey, B., Bowden, K., Shaul, Y., Petricoin, E., Caswell, S. V., Alhammad, R., Elayadi, A. N., Roberts, B., Martin, J.2026-03-02❤️ physiology

A Translational Model of MASLD-Associated HFpEF Defines Mitochondrial Dysfunction and Cardiac Plasticity During Disease Progression and Regression

This study establishes the Alms1-/- (Foz/Foz) mouse model as a robust translational platform demonstrating that mitochondrial dysfunction and fibroinflammatory remodeling drive MASLD-associated HFpEF, a condition characterized by reversible cardiac and hepatic phenotypes upon dietary intervention.

Ganguly, S., Gunes, B., Gu, Y., Suarez, J., Gupta, G., Ishizuka, K., Murad, R., Kisseleva, T., Dillmann, W., Peterson, K., Adler, E., Brenner, D., Dhar, D.2026-02-28❤️ physiology

Cardiac synchrony during collaborative drawing: A longitudinal comparison of same generation and intergenerational dyads

This longitudinal study of collaborative drawing programs found that while interpersonal distance and self-reported closeness effectively characterized relationship development in both intergenerational and same-generation dyads, cardiac synchrony showed only a marginal link to active collaboration specifically within intergenerational pairs.

Moffat, R., Naudszus, L. A., Cross, E. S.2026-02-26❤️ physiology