3881 papers
This study assembled and annotated the complete plastomes of five medicinally important *Caragana* species, revealing conserved genomic features, identifying hypervariable regions, and providing a phylogenetic framework that challenges existing taxonomic classifications to support future germplasm conservation and sustainable utilization.
This study introduces a multi-stage robust framework for hyperscanning EEG analysis that effectively filters environmental and motor confounds to reveal how beta and gamma band inter-brain connectivity dynamically reconfigures between leader and follower roles during musical rehearsal versus rhythmic performance.
This study reveals that *Sphingomonas sanguinis* isolates from the International Space Station harbor a conserved, plasmid-linked mercury resistance operon absent in terrestrial counterparts, suggesting this mobile genetic element facilitates their long-term persistence in the closed space habitat.
This study utilizes shotgun metagenomics to reveal the functional heterogeneity of Yucatan Peninsula coastal microbial mats, demonstrating that specific mat types and locations exhibit distinct potentials for methane, sulfur, and nitrogen metabolism that directly influence greenhouse gas emissions and nutrient cycling.
This study found that while acute bouts of both HIIT and MICT did not significantly alter circulating catestatin or chromogranin A levels in sedentary young males, baseline catestatin levels were selectively and positively correlated with early heart rate recovery specifically following high-intensity interval training, suggesting a potential modulatory role in post-exercise parasympathetic reactivation.
This study demonstrates that targeted deletion of Connexin 43 (Cx43) in either podocytes or endothelial cells protects against experimental glomerulonephritis, with endothelial-specific deletion providing superior protection, thereby establishing Cx43 as a critical mediator of glomerular injury and a promising therapeutic target.
This study detected a diverse array of zoonotic bacterial pathogens in 18% of bats sampled from Brazilian Cerrado veredas, revealing distinct host-pathogen interaction networks between preserved and degraded habitats and highlighting the critical role of ecological context in wildlife disease surveillance under the One Health framework.
This study integrates Mendelian randomization, single-cell transcriptomics, and machine learning to establish a causal link between hyperhomocysteinemia and ischemic stroke, identifying macrophages as the key cell type and Gusb, Rab2a, and Mrpl36 as critical diagnostic genes driving neuroinflammation.
This study demonstrates that the indoor resting patterns of *Anopheles funestus* in southeastern Tanzania are significantly shaped by microclimatic gradients driven by housing materials, with mosquito abundance peaking in brick-walled, grass-thatched houses near the floor where specific combinations of temperature, absolute humidity, and minimal thermal fluctuations create optimal resting niches.
This study developed and validated a 102-gene transcriptomic signature, TGx-HDACi-HepaRG, which achieves 100% accuracy in classifying histone deacetylase inhibitors within human HepaRG liver cells, offering a promising animal-free biomarker for chemical risk assessment pending further external validation.