🧬 Category

q-bio

1625 papers

🧬 biology

Core functional convergence and spatiotemporal complementarity of soil microbial communities between rhizosphere and decomposing habitats in Foding Mountain Nature Reserve, China

This study reveals that in the Foding Mountain Nature Reserve, host plants exert bidirectional regulation on rhizosphere microbiomes while fungi and bacteria employ a spatiotemporal complementary strategy with distinct functional roles during organic matter decomposition, collectively driving material cycling and functional maintenance in subtropical forest ecosystems.

Jinhua Xu, Xinghong Wang, Anxiong Wei, Qingsong Ran, Haiyan Wang, Chunbo Dong, Yanwei Zhang, Wanhao Chen, Yanfeng Han2026-07-06
🧬 biology

Neuronal Mitochondrial Dysfunction Drives Astrocytic Mitochondrial Transfer after TBI: Reveals the Therapeutic Potential of astrocytic EV-Mito

Following traumatic brain injury, neuronal mitochondrial dysfunction triggers an adaptive astrocyte-mediated response where mitochondria are transferred via extracellular vesicles to restore somatic and neuritic bioenergetics, though this protective mechanism fails to reach synapses.

Gopal V Velmurugan, Hemendra J Vekaria, Alexander G Rabchevsky, Kai Saito, Josh M Morganti, Samir Patel, Brad Hubbard, P (…)2026-07-06
🧬 biology

SpikeTrainPatternDetector: a provenance-aware R/Shiny framework for neuronal firing-pattern detection and review

SpikeTrainPatternDetector (STPD) is an open-source R/Shiny framework designed to preserve the provenance of neuronal firing-pattern detection decisions through automated candidate generation, deterministic conflict resolution, and manual review, serving as a reproducible infrastructure for expert validation rather than a standalone biological classifier.

Houchun Zhou, Alexey Sedov2026-07-06
🧬 biology

Root water-uptake depth and leaf trait adjustments along a water table gradient: trade-offs among trees and shrubs in a tropical coastal forest

This study demonstrates that in tropical coastal restinga forests, trees and shrubs adjust their root water-uptake depth in response to water table levels to maintain water status, but this belowground investment creates a trade-off that specifically constrains aboveground photosynthetic traits and greenness in trees.

Cristina Antunes, Sergio Chozas, Rafael Flora, Cristina Máguas, Carlos Joly, Simone Vieira2026-07-06
🧬 biology

Sublethal Toxicity of Chlorpyrifos in the Freshwater Fish Puntius chola: Integrated Assessment of Behavioral Responses, Biochemical Alterations, and Histopathological Damage

This study demonstrates that sublethal exposure to the organophosphate insecticide chlorpyrifos induces significant metabolic stress, biochemical imbalances in carbohydrate and lipid profiles, and severe multi-organ histopathological damage in the freshwater fish *Puntius chola*, highlighting its potential as a sensitive biomarker for monitoring pesticide contamination in aquatic ecosystems.

Balaganesh Balakumar, Thangaraj Sangappillai, Stalin Arumugam, Gokula Varadharajan2026-07-06
🧬 biology

Streamline-Based Analysis: A novel framework for tractogram-driven streamline-wise statistical inference

This paper introduces Streamline-Based Analysis (SBA), a novel non-parametric framework that performs statistical inference directly on individual tractography streamlines to achieve high-resolution, whole-brain white matter analysis with family-wise error control, thereby bridging the gap between voxel-, fixel-, and tract-level methods.

Simone Zanoni, Jinglei Lv, Sharon Naismith, Robert Smith, Fernando Calamante2026-07-06
🧬 biology

Adipocyte GDI2 suppresses lipophagy to restrain adaptive thermogenesis and promotes diet-induced obesity

This study identifies GDI2 as a critical inhibitor of adipocyte lipophagy that suppresses beige fat thermogenesis and promotes diet-induced obesity, demonstrating that its deletion enhances lipid degradation and metabolic health by activating a PPARα/PGC1α-dependent transcriptional program.

Fei Gao, Yongjiao Zhang, Dong Liu, Yufan Song, Yang Sun, Meitian Wang, Sumei Lu, Guangyong Zhang2026-07-06
🧬 biology

A z-averaged ensemble of three orthogonal models improves protein–ligand virtual screening on leakage-controlled benchmarks

This paper demonstrates that a z-averaged ensemble of three representationally orthogonal deep-learning models significantly improves protein–ligand virtual screening performance on leakage-controlled benchmarks by achieving genuine out-of-distribution generalization, thereby overcoming the limitations of single-model approaches on novel targets.

Yuguang Mu, Yang Liu, weifeng li2026-07-06
🧬 biology

Bioacoustics: Deep-Learning Model Selection, Optimization, and Deployment for Wildlife Sound Classification on Edge Devices

This paper presents a reproducible, end-to-end workflow for selecting, optimizing, and deploying accurate, auditable bioacoustics models on CPU-only edge devices, utilizing a specific architecture of log-mel spectrograms, vision-pretrained CNNs, and attention mechanisms to overcome real-world challenges like noise and domain shift while validated on the BirdCLEF+ 2026 Pantanal benchmark.

Rommel Sharma2026-07-06