1625 papers
The bacterium *Rhodococcus ruber* SiAl demonstrates highly selective and efficient removal of iron (up to 99%) and phosphate from culture media, a capability supported by identified siderophore and phosphate transport genes, while showing minimal magnesium uptake and growth inhibition by manganese.
This study developed a simple and practical cultivar identification system for Japanese pummelo using 18 selected InDel markers detectable via standard PCR and gel electrophoresis, which not only enables efficient protection of breeders' rights but also provides insights into the genetic relationships and parentage of key cultivars.
The paper introduces AIGCRS-AMP30, an integrated AI framework that combines diffusion-based generation, classification, and regression models to design short, potent antimicrobial peptides, which were experimentally validated to show high efficacy against multidrug-resistant pathogens with low host toxicity.
The paper proposes a model where the transbilayer distribution of plasma membrane cholesterol is determined by the stoichiometric complexation of sterols with leaflet-specific phospholipids, predicting that the outer leaflet contains approximately two-thirds of the total cholesterol due to its higher cholesterol-to-phospholipid ratio.
This study introduces NDPAI, a neuroscience-inspired active inference framework that achieves competitive cross-subject wearable stress detection while providing superior probability calibration, interpretable decision-making, and adaptive computational efficiency through a dual-pathway architecture governed by Variational Free Energy routing.
This study analyzes a large multi-ethnic cohort to demonstrate that fractal motor activity regulation is significantly influenced by age, sex, physical activity levels, and race/ethnicity, with distinct patterns observed across different demographic groups that could enhance early Alzheimer's disease detection.
This study integrates transcriptomic data to identify mitochondrial dysfunction-associated genes in NAFLD, establishing a high-accuracy diagnostic model and uncovering novel therapeutic targets and immune microenvironment interactions.
This study demonstrates that Chuangyu Liquid promotes cutaneous wound healing by modulating an AKT1-centered regulatory network, a mechanism identified through network pharmacology, molecular docking, and validated by in vivo experiments showing increased Akt1 mRNA and AKT protein levels.
This study demonstrates that low TSG101 expression in clear cell renal cell carcinoma (ccRCC) is associated with malignant progression, poor prognosis, and an immunosuppressive landscape, suggesting its potential as a prognostic biomarker and therapeutic target.
This study identifies the highly conserved effector AvrYr28-01 as the target of the wheat immune receptor Yr28, explaining its broad-spectrum and potentially durable resistance against stripe rust despite the presence of unrecognized paralogous variants and age-dependent resistance suppression.