1625 papers
This paper proposes an optimal control strategy for an SEIVZ epidemic model incorporating Holling-IV incidence and information intervention, demonstrating that while the disease-free equilibrium is stable when with a backward bifurcation at , the combined application of information and treatment controls effectively mitigates disease spread while minimizing associated costs.
This study characterizes the spectral irradiance of various indoor lighting systems and backlit electronic devices, revealing that their blue-rich emissions can suppress human melatonin levels significantly within minutes to hours, thereby posing a substantial risk to circadian rhythms in typical professional and educational environments.
This systematic review of 29 studies involving adults aged 60 and older demonstrates that physical activity, particularly aerobic, resistance, and open-skill exercises, significantly enhances attentional functions and supports broader cognitive health in aging populations, offering a scalable strategy to mitigate cognitive decline.
SCPInt is a deep-learning framework that integrates heterogeneous single-cell proteomics datasets by explicitly disentangling biological and batch variations, thereby outperforming existing methods in preserving biological structure while providing quantitative insights into technical biases for scalable atlas construction.
This study demonstrates that repeated exposure to anthropogenic noise induces transient, time-dependent fluctuations in serum glucose levels in male Mongolian gerbils, while having less consistent effects on urea, cholesterol, and body mass, thereby highlighting the specific metabolic impact of acoustic pollution and the importance of monitoring post-exposure recovery dynamics.
This paper presents the Nine-Dimensional Weighted Computing Model (9-WCM), an AI-driven framework that integrates nine biological pillars and ESM-Fold protein structure analysis to generate a unified, topologically visualized biological age index for more accurate systemic aging assessment and health management.
Rifampicin treatment of in vitro grapevine cultures disrupts the dominance of *Mycobacterium* and restructures the endophytic community into a more even, heterogeneous assemblage without establishing a new dominant taxon, supporting a model of dominance relaxation and non-convergent reassembly.
This study reveals that in Central European fishponds, avian predators—particularly marsh harriers—are the primary drivers of duck nest predation, with risk levels significantly influenced by nest-specific factors like incubation stage and prior depredation, as well as varying spatial and temporal dynamics specific to predator groups.
This study demonstrates that Daikenchuto (DKT) improves colonic motility and modulates sex-specific gut microbiota in a mouse model of congenital hypoganglionosis, suggesting its potential therapeutic efficacy for this disorder.
This study demonstrates that FAM20A deficiency causes impaired alveolar bone formation in enamel–renal syndrome by disrupting Wnt signaling, a mechanism that can be partially rescued by pharmacological activation of the pathway.