1625 papers
This study reveals that while the invasive species *Ageratum conyzoides* and *Chromolaena odorata* achieve reproductive success through pollinator-independent strategies, *Mikania micrantha* relies more heavily on pollinator-mediated reproduction alongside vegetative propagation for its invasion success in the Eastern Himalaya.
This study demonstrates that cell surface desialylation attenuates EGFR-mediated signaling by disrupting specific N-glycan-phosphorylation interactions and distinctively suppressing MAPK and cytoskeletal pathways, thereby revealing glycan remodeling as a potent strategy to sensitize RTK-driven malignancies to therapy.
Despite an intensive 18-month field study in southeastern Gabon involving over 12,000 trap-nights, researchers failed to capture or detect *Plasmodium* infections in the thicket rat *Grammomys poensis*, suggesting that local transmission may be absent or severely constrained compared to historical reports and highlighting the urgent need for contemporary field isolates to improve rodent malaria research models.
This study utilizes deep mutational profiling of normal lung tissue to demonstrate that aging, smoking, and anti-cancer therapies drive context-dependent clonal selection, revealing distinct mutational landscapes and convergent evolution that differ significantly from those observed in lung cancers.
This study on wild Western Australian magpies demonstrates that problem-solving performance requires testing beyond chance levels to be meaningful and reveals no correlation between an individual's ability to solve novel puzzles and their associative learning scores, challenging the assumed link between these two cognitive traits.
This paper introduces a generative causal representation learning method that successfully separates stimulation artifacts from therapeutic signals in Parkinson's disease deep brain stimulation, enabling the identification of a stimulation-orthogonal neural biomarker that accurately tracks motor improvement without supervision of clinical outcomes.
This study presents the first national cohort analysis of 648 individuals in the Dominican Republic, characterizing a distinct spectrum of 15 pathogenic BRCA1/BRCA2 variants to improve genomic representation, variant interpretation, and precision medicine for Caribbean populations.
This study utilizes molecular dynamics simulations to demonstrate that gain- and loss-of-function mutations in *Euglena gracilis* phytoene synthase alter carotenoid production by inducing distinct conformational remodeling of the enzyme's energy landscape, residue mobility, and active-site architecture.
This study systematically identifies and characterizes the eight KNOX genes in *Eucommia ulmoides*, revealing their phylogenetic classification, tissue-specific expression patterns, and distinct regulatory roles in development and responses to various phytohormones and abiotic stresses.
This study employs a comprehensive computational workflow to characterize WWV93726.1, a conserved hypothetical protein from the jumbo phage vB_Pae3705-KEN49, identifying it as a non-canonical, bimodular DNA-binding regulatory protein that likely governs the transition from phage transcription to assembly through an electrostatically driven interaction with viral promoter sequences.