1686 papers
This study demonstrates that free-ranging wild boars in a Mediterranean ecosystem exhibit significantly elevated circulating IL-6 concentrations compared to intensively reared domestic pigs, identifying IL-6 as a robust immune marker reflecting the distinct inflammatory tone shaped by ecological conditions at the wildlife–livestock interface.
This study demonstrates that while resolving cognitive conflict in 2D Spatial Stroop tasks reliably triggers transient reductions in force moment variability as a sign of shared processing capacity, the specific body axis affected does not strictly align with the direction of manual decision-making, suggesting that cognitive-balance interference is shaped by broader sensorimotor factors like attention shifts rather than just the decision frame of reference.
This study presents the first extensive comparative analysis of silk-spinning systems in 40 corophiidan amphipod species, revealing a conserved ancestral framework alongside multiple independent evolutionary origins of modified structures that co-evolved with strong attachment silk, thereby establishing these crustaceans as a critical model for understanding the diversification of silk-spinning systems beyond insects and spiders.
This study demonstrates that while larvicidal oil poses a severe lethal and sublethal threat to the endangered Romer's Tree Frog, Bacillus thuringiensis israelensis (Bti) and temephos are safer alternatives for urban mosquito control, highlighting the critical need to evaluate both acute and prolonged exposure effects in ecological risk assessments.
This study demonstrates that spontaneous speech analysis serves as a scalable digital biomarker with sensitivity to within-person cognitive change comparable to standard brief cognitive assessments, validating its potential for monitoring early cognitive decline in older adults.
This study reports the first successful expression of the raffinose-hydrolyzing enzyme InvDz13 in *Bacillus subtilis*, achieving a record-high extracellular activity of 568.86 U/mL through a multidimensional combinatorial strategy involving chassis engineering, promoter optimization, signal peptide screening, and secretion pathway regulation.
This study demonstrates that the recombinant depolymerase Dp3, derived from the novel K62-specific phage IME328, effectively eradicates multidrug-resistant *Klebsiella pneumoniae* by synergizing with serum and enhancing macrophage function, ultimately providing 100% survival in a lethal murine bacteremia model.
This study demonstrates that in grapevine cells, the overexpression of phosphoenolpyruvate carboxylase kinases (VvPPCKs) enhances PEPC activity while negatively regulating the stress-induced biosynthesis of the defense compound resveratrol, whereas silencing these kinases has the opposite effect.
This study identifies the R1398 residue as a critical GTP-γ-phosphate sensor that regulates the conformational switching of the LRRK2 ROC domain, demonstrating that the protective R1398H mutation stabilizes an inactive GDP-bound state by impairing GTP-state stabilization and offering a novel therapeutic strategy for Parkinson's disease targeting the GTPase domain rather than the kinase active site.
This study introduces and validates a network propagation framework on a bipartite metabolite–reaction graph that diffuses statistical signals across the metabolic topology to enhance the exploration of partially observed metabolomic data, improve multivariate predictive performance, and facilitate hypothesis generation beyond traditional pathway-based approaches.