🧬 Category

q-bio

1754 papers

🧬 biology

Predicting Microbiologically Influenced Corrosion Risk from Quorum Sensing Biofilm Community Features: A Random Forest-SHAP Approach

This study introduces a Random Forest-SHAP machine learning framework that successfully predicts microbiologically influenced corrosion risk by integrating novel quorum sensing biofilm community features with traditional environmental and microbial parameters, achieving an F1 score of 0.762 and demonstrating the predictive value of bacterial communication signals in corrosion assessment.

Bipul Bhattarai, Naina Maharajan, Sulav Dahal2026-07-01
🧬 biology

AI-Based Pipeline for Vascularization Detection in Histological Images; low-cost solution Using Moderate Computing Resources

This paper presents a low-cost, user-friendly AI pipeline that combines simple image processing with an interactive, self-learning similarity-search method to enable pathologists to rapidly and accurately detect vascularization in histological images using modest computing resources and minimal manual labeling.

Jan Žídek, Bretislav Lipový, Veronika Pavliňáková, Martin Knoz, Jakub Holoubek, David Izsák, Vladimir Váňa, Jan Herudek (…)2026-07-01
🧬 biology

Ecological Inference Is Structured Empirical Risk Minimization: Generalization Across Space, Nested Units, and Niche Support

This paper argues that the frequent failure of geographic models to generalize across sites stems from a fundamental estimand mismatch in nested survey data, demonstrating that ecological inference is structurally equivalent to empirical risk minimization under domain generalization and requiring population-level holdout validation rather than standard individual-level cross-validation to ensure reliable spatial transfer.

R. Craig Stillwell2026-07-01
🧬 biology

BioGPT-ClinVar: Parameter-Efficient Fine-Tuning of a Biomedical LLM for Genomic Variant Interpretation

This study presents BioGPT-ClinVar, a parameter-efficient fine-tuning framework using Low-Rank Adaptation (LoRA) to adapt the 150-million-parameter BioGPT model for genomic variant interpretation, demonstrating effective convergence on a curated ClinVar dataset while providing an open-source, reproducible pipeline for future clinical and surveillance applications.

Sepideh Moafi2026-07-01
🧬 biology

Trained quantum Kolmogorov--Arnold networks can dequantize, and a discrete-logarithm encoding need not: a measurement-based map of where quantum advantage can live

This paper demonstrates that while trained quantum Kolmogorov–Arnold networks are often classically simulable via low-bond-dimension tensor networks, genuine quantum advantage can be preserved and made trainable by employing discrete-logarithm encodings that embed number-theoretic hardness without succumbing to barren plateaus.

Hikaru Wakaura2026-07-01
🧬 biology

Xkr regulates phosphatidylserine transport via ER-PM contact sites to promote apoptotic cell clearance

This study reveals that the Drosophila lipid scramblase Xkr promotes apoptotic cell clearance by interacting with dORP9 at ER-plasma membrane contact sites to facilitate non-vesicular phosphatidylserine transport to the cell surface, thereby serving as an alternative caspase-independent pathway for "eat me" signal exposure.

Qian Zheng, Xinyu Ma, Fuqiao Liu, Tong Xiao, Lei Yuan, Qing Yan, Hui Wang, Hui Xiao2026-07-01
🧬 biology

Analysis of Human Physiology in Simulated Lunar and Martian Hypogravity With and Without Virtual Reality

This study demonstrates that simulated hypogravity reduces cardiovascular demand during walking while virtual reality modulates physiological responses by delaying heart rate increases, confirming the safety and efficacy of combining AlterG treadmills with VR for preparing crews for future lunar and Martian missions.

Rosirene Pantaleão Gessinger, Juliana Silva Herbert, João de Carvalho Castro, Joana Figueira Godinho, Adrian Alberto Fer (…)2026-07-01
🧬 biology

Intrasexual competition modulates heatwave effects on male reproduction in Drosophila prolongata

Contrary to expectations, this study reveals that intense intrasexual competition partially mitigates the negative impact of heatwaves on male reproductive output in *Drosophila prolongata*, likely through a compensatory increase in reproductive investment, highlighting the critical role of interactive environmental stressors in shaping wildlife responses to climate change.

Shivanshi Gupta, Gayatri Raina, Marta Cortés Mediavilla, Tom Ratz2026-07-01
🧬 biology

Tracing the Evolution and Circulation of Measles Virus in Africa

This study utilizes phylodynamic analysis of 336 measles virus strains to reveal that African transmission is driven by human mobility and frequent Asian introductions, characterized by prolonged cryptic circulation that underscores the urgent need for enhanced surveillance and vaccination to prevent global spread.

Nidia Trovao, Sana Tamim, Herve Kadjo, Samiah Kanwar, Anna Salafsky, Olayinka Okoh, Marius Adagba, Yakoura Ouattara, Ven (…)2026-07-01