3881 papers
This study identifies a shared rare missense variant near the TUBA1C gene on chromosome 12 that links sudden sensorineural hearing loss and vestibular neuritis to disrupted serum potassium homeostasis, suggesting a common underlying mechanism for these inner-ear disorders.
This study identifies and characterizes the stage- and region-specific expression of conserved developmental regulators, particularly AP2/AIL transcription factors and chromatin modifiers, in the apogamic center of *Dryopteris affinis* gametophytes, linking their spatial localization to the initiation of sporophyte development without fertilization.
This study reveals that fishing cats in South Asia primarily rely on wetland and grassland habitats rather than avoiding large carnivores like tigers and leopards, suggesting that conserving these specific habitat mosaics alongside large carnivore populations is crucial for the species' persistence.
This study validates that task-related high-frequency activity in scalp EEG reflects underlying cortical processing by demonstrating significant concordance with concurrent intracranial EEG during working memory tasks and showing that an iEEG-guided knowledge distillation framework significantly improves non-invasive cognitive decoding performance.
This study demonstrates that while unsupervised clustering of handcrafted morphological and textural descriptors can reveal a modest signal distinguishing benign from malignant breast cancer in a label-free setting, the resulting performance remains insufficient for clinical diagnostic use.
This paper introduces an iterative moving-window framework for analyzing recursive movements in wildlife and livestock tracking data, demonstrating its utility in revealing ecological patterns such as seasonal migration strategies, site fidelity mechanisms, and habitat utilization across multiple species.
By integrating protein-protein interaction networks with human hepatic transcriptomics, this study identifies PGC-1α as a central, repressed hub within the 3,5-diiodo-L-thyronine–responsive metabolic network, establishing it as a key mechanistic target for treating metabolic dysfunction-associated steatotic liver disease.
This study presents a comparative whole-ORF evolutionary analysis of the seven canonical Bundibugyo ebolavirus proteins across the 2007, 2012, and 2026 outbreaks, revealing distinct protein-specific temporal substitution patterns and establishing a comprehensive reference framework for future genomic surveillance.
Recent research demonstrated that a three-channel laser back-scattering readout, measuring intensity and beam position, can effectively detect, quantify, and classify disease-linked breath-metabolite mixtures by generating distinct scatter signatures, thereby establishing a scalable method for breath-based health screening.
This study reveals that the human plasma proteome maintains aggregation resistance despite high abundance and β-sheet richness by evolving a restricted repertoire of recurrent β-sheet-rich domains with specific surface signatures that minimize amyloidogenic edge interactions.