3881 papers
This study validates a pig model for rotational acceleration traumatic brain injury by demonstrating high kinematic transfer efficiency (over 93% matching) between the injury device and the subject's head, confirming that the model accurately replicates human-relevant injury thresholds.
This study provides behavioral evidence that *Drosophila melanogaster* exhibits uncertainty-sensitive processing through increased decision and checking latencies in response to visual uncertainty, a regulatory mechanism that is significantly impaired when mushroom body neurons are silenced.
This study reveals that Siglec-15 drives a feed-forward loop in triple-negative breast cancer by activating the NF-κB/DcR3 pathway to induce M2-like macrophage polarization and CCL18 secretion, which in turn enhances Siglec-15 expression via STAT3 phosphorylation to further promote tumor progression.
This study replicated and extended Karnath et al. (2019) by using virtual reality and galvanic vestibular stimulation on twenty healthy participants, ultimately confirming that neither DC nor AC GVS significantly modulates perceived arm size, while also failing to replicate the original study's finding regarding body side effects.
This study characterizes the phenology, floral biology, and reproductive strategies of the threatened medicinal herb *Aconitum violaceum* in the Northwestern Himalaya, revealing its biennial life cycle, high reliance on *Bombus* pollinators for cross-fertile reproduction, and providing essential data for its conservation and sustainable utilization.
This study introduces PF-Map, a probe-free proximity labeling strategy utilizing an organic photocatalyst (IDM) to generate hydroxyl and superoxide radicals that dioxidize proximal histidine residues into stable, chemically addressable states, thereby enabling minimally biased spatial proteome mapping in live cells and revealing hidden vesicle trafficking subproteomes missed by traditional probe-dependent methods.
This study demonstrates that peripheral Foxp3+ regulatory T cell depletion triggers sex-specific hippocampal inflammasome activation and affective behavioral deficits, which are selectively attenuated by bioactive dietary polyphenols in male but not female subjects.
This study genomically characterizes a *Pseudomonas aeruginosa* isolate from an invasive catfish in Bangladesh's polluted Buriganga River, revealing its potential for bioremediating hydrocarbons and heavy metals while highlighting significant biosafety concerns due to its pathogenicity.
The aqueous extract of *Sambucus nigra* L. flowers protects oxidatively stressed HT-22 hippocampal cells by primarily restoring redox homeostasis through antioxidant mechanisms, while also modulating autophagy and the ubiquitin-proteasome system to enhance cell viability.
This study reveals that the transition from the beating heart primordium to the primitive heart tube in rats involves coordinated upregulation of mitochondrial metabolism proteins, particularly those in the tricarboxylic acid cycle, likely driven by insulin-like growth factor 2 to support the increasing energetic demands of early cardiac development.