1754 papers
A study of a Mediterranean *Pinus halepensis* forest in Israel reveals that while moderate thinning slightly reduces total fungal diversity, complete tree removal significantly alters soil characteristics and shifts fungal communities from symbiotic, pine-associated species to saprotrophic and pathogenic taxa typical of non-forested areas.
This study presents a multi-omics dataset integrating longitudinal transcriptomic and microbiome profiles from wild-type and IgZ knockout zebrafish to elucidate the developmental role of IgZ in regulating gut immunity and microbial homeostasis.
This study demonstrates that systematically optimizing the 5' untranslated region and codon usage of mRNA vaccines significantly enhances protein expression levels and stability, a strategy validated through successful design and testing of respiratory syncytial virus (RSV) F protein vaccines.
This study integrates single-cell and bulk transcriptomic analyses with Shennong machine learning to identify an eight-gene calmodulin-related prognostic signature in breast cancer, revealing its association with epithelial cell dynamics, specific signaling pathways, and potential therapeutic targets.
This study presents the first transcriptome-wide analysis of Australasian snapper gonads throughout their reproductive cycle, revealing sex-specific gene expression patterns in steroidogenic enzymes and developmental processes while simultaneously improving the species' genome annotation to support future aquaculture and reproductive research.
This study demonstrates that Aster-mediated non-vesicular transport and endocytic pathways are critical for the intestinal absorption and human bioavailability of fat-soluble vitamins D and E, while vitamin A utilizes an Aster-independent route.
This study demonstrates that submillimeter-resolution postmortem and in vivo diffusion and susceptibility MRI metrics exhibit moderate correspondence in characterizing human cortical micro- and meso-structures, providing a comprehensive anatomical reference to bridge high-fidelity postmortem imaging with in vivo neuroimaging applications.
This study utilizes integrated transcriptomic and metabolomic analyses to reveal that *Enterocytozoon hepatopenaei* infection in *Litopenaeus vannamei* drives growth retardation through ribosomal suppression and manipulates lipid metabolism and immune signaling, potentially by hijacking host membrane synthesis resources for spore formation.
This study characterizes a multidrug-resistant *Klebsiella quasipneumoniae* subsp. *similipneumoniae* strain isolated from a Malaysian dog shelter with a history of prolonged co-amoxiclav use, revealing a distinct microbial profile between fecal and drainage samples and highlighting critical gaps in antimicrobial stewardship within the One Health context.
Chronic exposure to environmentally relevant concentrations of fluoride and tebuconazole disrupts the alpha and beta diversity, co-occurrence networks, and taxonomic composition of gill, skin, and gut microbiomes in rainbow trout, leading to an enrichment of pathogenic and antibiotic-resistant bacteria that may compromise host health and broader ecosystem stability.