🧬 Category

q-bio

1816 papers

🧬 biology

Valorization of Freshwater Crab Derived Astaxanthin from Spiralothelphusa hydrodroma (Herbst, 1794) with Enhanced Antioxidant and Antibacterial Efficiency

This study demonstrates that the shells of the freshwater crab *Spiralothelphusa hydrodroma* serve as a superior natural source of astaxanthin compared to its tissues, exhibiting high extraction yields and significant antioxidant and antibacterial activities that support their potential use in nutraceutical and pharmaceutical applications.

Shanthi Rangasamy, Sowmiya Sundararajan, Monica Prakash, Sivakumar Mullaivanam Ramasamy2026-06-26
🧬 biology

ResVGGFormer: A Hybrid Residual-enhanced VGG-Transformer model for Predicting Multi-type RNA Modification Site in S. cerevisiae

This paper introduces ResVGGFormer, a hybrid deep learning framework that combines a residual-enhanced VGG-style backbone with a Transformer encoder to efficiently and accurately predict multi-type RNA modification sites in *S. cerevisiae*, achieving state-of-the-art performance and superior training efficiency compared to existing baselines.

Wei Liu, Kaiyang Li, Xiangzhi Wang, Le Ding, Shuo Xu, Yan Yang, Rui Zhang, Tongnan Yin2026-06-26
🧬 biology

The Invisible Engine of Cymbidium goeringii Nutritional Growth - Mycorrhizal Symbiosis

This study identifies a specific *Ceratobasidiaceae* fungus (KMGT47) isolated from the photosynthetic orchid *Cymbidium goeringii* as being identical to an ectomycorrhizal fungus of *Pinus yunnanensis*, thereby providing the first evidence of a tripartite symbiosis where carbon is transferred from the pine to the orchid via shared fungal hyphae.

Jianxin Chen, Xiang Ma, Fengjinglin Wu, Youjiao Zhu, Fang Wang, Xingliang Xu, Jianrong Wu2026-06-26
🧬 biology

Prefrontal pyramidal neuron dysregulation impairs prefrontal-thalamic circuit function and underlies working memory retrieval deficits in Alzheimer’s disease

This study demonstrates that dysregulation of prefrontal pyramidal neurons disrupts mPFC-thalamic circuit function and impairs working memory in Alzheimer's disease, but that optogenetic restoration of these neurons' excitability can rescue circuit dynamics and cognitive deficits.

shengnan Zhang, Liusi Gong, Tiaotiao Liu, Aili Liu, Xin Tian, Xuyuan Zheng, Wenwen Bai2026-06-26
🧬 biology

Endocrine-Microbial Trade-offs under Extreme Cold and Physical Stress: Multi-omics Network Reveals Tryptophan/Lipid Reprogramming and the Cost of Cortisol Overload

This multi-omics study reveals that under extreme cold and physical stress, high-endurance individuals maintain metabolic stability through a "metabolic trade-off" strategy that prioritizes lipid mobilization and Christensenellaceae enrichment at the cost of local intestinal immunity, whereas maladapted individuals suffer from cortisol overload, Fusobacterium proliferation, and systemic inflammation.

Haonan Sun, Lixia Yu, Jiafan Liang, Jiahui Chen, Guoping Zhao, Zhanxin Yao, Yanbo Wang2026-06-26
🧬 biology

A Hybrid Grey Wolf Optimizer and Differential Evolution Wrapper for Descriptor Selection in QSAR Modelling

This paper proposes a hybrid Grey Wolf Optimizer and Differential Evolution wrapper for descriptor selection in QSAR modelling, demonstrating that while the method significantly improves predictive accuracy and reduces dimensionality on high-redundancy solubility datasets, its benefits are dataset-dependent and do not universally outperform regularized full-descriptor models.

Suprava Ghosh, Mrinal Kanti Rajak2026-06-26
🧬 biology

Cross-individual generalizability of machine learning models for ball speed prediction in baseball pitching

This study evaluates the cross-individual generalizability of machine learning models for predicting baseball pitch speed across 50 pitchers, revealing that while within-individual performance is high, generalization drops significantly and varies by expertise level and specific body segments, highlighting the need for cross-individual validation to improve practical applicability in sports science.

Ryota Takamido, Chiharu Suzuki, Hiroki Nakamoto2026-06-26
🧬 biology

Fear of the new: a predatory invader provokes stronger non-consumptive effects on a keystone native prey than a native predator

This study demonstrates that the invasive brown bullhead catfish induces stronger non-consumptive effects on the native keystone freshwater crayfish *Paranephrops planifrons* than the native longfin eel, likely due to the crayfish's heightened fear response to unfamiliar predator cues, posing a significant ecological threat as the invader's range expands.

Olivier Valentijn Raven, Calum MacNeil, Finnbar Lee, Robin Holmes, Ian A. K. Kusabs, Francis J. Burdon, Deniz Özkundakci2026-06-26
🧬 biology

Differences in root architecture influence the persistence time of competing species in simulated plant communities

Using a functional-structural plant model, this study demonstrates that greater divergence in root architecture extends the persistence time of competing plant species through density-dependent recovery mechanisms, whereas ecologically identical species rely on neutral drift for their persistence.

Hugo Salinas, Erik J. Veneklaas, Elizabeth Trevenen, Michael Renton2026-06-26