4041 papers
This study presents the first comprehensive transcriptomic analysis of novel duck reovirus (NDRV)-infected duck adherent PBMCs, revealing significant upregulation of immune-related and interferon-stimulated genes through RNA-Seq and validating these findings with real-time PCR to elucidate host-pathogen interactions and potential therapeutic targets.
This paper reports the first documented case of a male sedge wren in northern Illinois constructing a new nest atop an existing one, a behavior likely driven by habitat limitations in a fragmented, invasive grass-dominated environment.
This study presents a computationally engineered, self-assembling tetrameric scaffold based on the RSV M2-1 protein that successfully displays structurally preserved human metapneumovirus (HMPV) epitopes with high density and stability, achieving picomolar binding affinity with neutralizing antibodies and offering a promising dual-targeting strategy for next-generation pneumovirus vaccines.
This study presents cryo-EM structures of an engineered influenza-specific TCR/CD3 complex, revealing that peptide engagement induces localized conformational changes while preserving global architecture, and integrates lipidomics with computational modeling to identify novel lipid binding sites and affinity determinants for future immune modulation.
By applying a multi-method consensus framework to aquaponic microbiome data, this study found no universal keystone taxa, suggesting that ecological resilience is distributed across compartment-specific assemblages rather than concentrated in single organisms, thereby advocating for targeted monitoring of specific habitats like fish tanks and biofilms instead of seeking a single system-wide indicator.
This study identifies that forced treadmill running specifically activates D2-MSNs in the nucleus accumbens core, where enhanced excitability and synaptic transmission act as a central "braking signal" that limits exercise performance and promotes early termination.
This study proposes a three-stage framework combining YOLOv8m for detection, SAM for segmentation and feature extraction, and PCA-enhanced Euclidean distance analysis for global ID assignment, achieving 96.4% mAP50 and enabling unique identification of individual flamingos in aerial video streams.
This study characterizes the diversity, distribution, and abundance of native *Trichoderma* species across six agroecological zones in Tanzania's irrigated lowland rice systems, revealing that soil properties significantly influence community composition and identifying a rich reservoir of native isolates with potential for use as biocontrol agents.
By integrating microscopy with multi-omics data, this study characterizes a 2022 white plague outbreak in *Pseudodiploria strigosa* corals at Flower Garden Banks, revealing a complex pathology involving host-symbiont dysbiosis, immune stress, and viral enrichment while establishing a comprehensive framework for future marine disease research.
This study elucidates the molecular mechanisms of *Populus × euramericana*'s response to shading by integrating phenotypic and transcriptomic analyses to reveal how reduced light intensity alters growth and photosynthesis while activating specific regulatory pathways involving hormone signaling, light-responsive transcription factors, and the MAPK cascade.