4041 papers
This paper introduces \texttt{MASCAF}, a free, open-source, and topologically robust pipeline that automatically fits cable models to complex 3D neuronal surface meshes, including those with cyclic structures like toric spines, thereby bridging the gap between advanced neuronal imaging and high-resolution multicompartmental simulations.
This study reveals that the amoebicidal interaction between *Beauveria bassiana* and *Acanthamoeba castellanii* is a context-dependent, multifactorial process driven by the fungus's environmentally regulated secondary metabolism (particularly oosporein production) and stress responses, which trigger a coordinated transcriptional reorganization of cytoskeletal and stress pathways in the amoeba.
This study analyzes over 139,000 UK Biobank participants to confirm that the Autism-Spectrum Quotient (AQ) reliably replicates key findings regarding autistic diagnosis, sex differences, and STEM occupation associations, thereby validating its utility for investigating the biological influences of autistic traits in the general population.
This paper demonstrates that the standard genetic code's perceived exceptionalism is not an intrinsic property but a statistical artifact, as its rank among randomized alternatives fluctuates significantly depending on the specific mutation spectrum and the summary statistic used for comparison.
A field experiment in Barbados demonstrates that meso-herbivorous fish, which are specifically targeted by local fishing gear, are essential for suppressing algal biomass and maintaining crustose coralline algae, as smaller herbivores cannot compensate for their loss.
This study introduces a rapid, sensitive, and specific TaqMan qPCR method using V4 16S rRNA gene primers and LNA-modified probes to accurately quantify total and clade-specific *Endozoicomonas* abundances in coral hosts, with results strongly correlating to NGS data.
This study conducted in the Kashmir Himalaya reveals that the Himalayan Serow preferentially utilizes rocky slope habitats and exhibits seasonal dietary flexibility, consuming a diverse range of vegetation including specific grasses, shrubs, and trees, thereby underscoring the need to conserve varied vegetation communities and rugged terrain to support the species' survival.
This study demonstrates that type II alveolar pneumocytes accumulate at the periphery of osteosarcoma lung metastases and promote tumor growth through a pro-fibrotic, growth-permissive microenvironment, suggesting a novel therapeutic target for limiting metastatic progression in both human and canine patients.
This paper reveals that a previously overlooked hydropathic asymmetry between specific transversion pairs at the second codon position, which standard transition/transversion ratios fail to capture, is a fundamental feature of the genetic code's error minimization that significantly improves the prediction of evolutionary advantages across diverse species.
This study reveals a critical mismatch along China's land border where the availability of complete reference genomes for priority zoonoses correlates inversely with disease burden, reflecting pathogen notoriety rather than public health need and highlighting an urgent priority to sequence high-burden pathogens like brucellosis.