4120 papers
This study demonstrates that in cuttlefish, the intra-male reduction in sperm flagellar length during growth occurs despite the absence of insemination-site dimorphism, suggesting that the competitive pressures faced by smaller "sneaker" males drive the evolution of costly sperm traits independent of distinct sperm storage sites.
This study demonstrates that speech foundation models, particularly when utilizing intermediate-to-late encoder layers and soft-voting aggregation, outperform handcrafted acoustic features in detecting Parkinson's disease from sentence reading across two independent cohorts, though they still exhibit demographic performance disparities and show more variable results on sustained vowels.
Ancient genomic analysis of fossil remains from the Azores reveals that extinct giant chaffinch ecomorphs, which morphologically resembled Canary Islands blue chaffinches, actually evolved from the extant Azorean common chaffinch lineage, demonstrating that significant morphological divergence can occur without substantial genome-wide divergence.
IndepMR is a novel, open-source R Shiny framework that automates two-sample, multivariable, and mediation Mendelian Randomization analyses by integrating ontology-driven trait retrieval and a rigorous ancestry-matching engine to ensure reproducible causal inference using public GWAS summary data.
This study demonstrates that acute open-skill exercises like short tennis, particularly those involving visuomotor coordination and social interaction, enhance inhibitory control more effectively than walking, despite eliciting similar prefrontal cortex hemodynamics.
This study integrates bulk, single-cell, and spatial transcriptomics to demonstrate that a cell-cycle program score (CCPS) in early-stage lung adenocarcinoma predicts recurrence risk while correlating with an immune-engaged and immunoregulatory transcriptional context, though the findings do not yet establish clinical predictive utility or causal immune regulation.
HistAgent is a unified framework that combines a visual-omics foundation model with a spatial AI agentic module to infer, interpret, and retrieve spatial molecular information from routine H&E histology images, offering a cost-effective and generalizable alternative to expensive spatial transcriptomics while enabling traceable, question-driven biological analysis.
By analyzing a longitudinal panel of over 15,000 Boston Marathon runners, this study demonstrates that traditional cross-sectional comparisons significantly underestimate individual endurance performance decline—by approximately 50% at age 65—because they fail to account for the selective attrition of slower athletes who drop out of competition over time.
This study reveals that twin "connectedness" does not stem from continuous spontaneous brain synchronization but rather from latent neural similarities that emerge as enhanced task-evoked neural alignment and behavioral resonance when cognitive or emotional systems are engaged.
This in silico drug repurposing study identifies Aromasin as a promising candidate for treating Alzheimer's disease-associated synaptic dysfunction by demonstrating its ability to simultaneously and stably bind to COX-2 and iNOS, thereby modulating inflammatory and oxidative pathways through favorable pharmacokinetics and thermodynamic stability.