5760 papers
This study demonstrates that in the floating fern *Salvinia natans*, the growth advantage of moderate fragmentation over light or severe fragmentation is contingent on high resource availability, while different fragment configurations drive distinct patterns of trait coordination and network organization in response to varying light and nutrient conditions.
This study demonstrates that label-free potentiodynamic fingerprints generated during bacterial growth in blood cultures originate primarily from dynamic bacteria-electrode interfacial interactions, such as adhesion and local metabolic activity, rather than from bulk metabolic changes or acidification alone.
This study introduces an uncertainty-aware benchmarking framework that reveals significant inter-tool discordance in classifying lncRNAs and mRNAs, demonstrating that incorporating repeat-derived features and secondary structure analysis helps identify ambiguous transcripts and guides the development of more robust classifiers.
Quercetin and luteolin exert antitumor effects on MeWo melanoma cells by inducing apoptosis, arresting the cell cycle, and inhibiting migration through the modulation of GPER signaling pathways, as evidenced by altered expression of P-ERK, c-Myc, and P-Akt that is reversed by the GPER antagonist G15.
This paper introduces ResiScan, an explainable machine-learning framework that leverages ESM2 protein embeddings and logistic regression to rapidly and accurately classify antibiotic resistance genes into five major classes, achieving 99.25% accuracy while providing interpretable insights through SHAP analysis and an accessible web interface.
This study identifies a cluster of immune-associated nucleotide-binding (IAN) genes as negative regulators of pollen heatwave tolerance in *Arabidopsis* through a novel machine-learning-based phenotyping assay and genome-wide association study, suggesting them as potential targets for breeding climate-resilient crops.
This study developed a five-gene prognostic risk model based on carnitine-related genes (ALPL, RAB38, SLC4A8, ZMAT4, and IGLON5) to stratify ovarian cancer patients into high- and low-risk groups, revealing significant associations with survival outcomes, immune infiltration, and drug sensitivity.
This study demonstrates that microhabitat heterogeneity, particularly through functional traits like chelae morphology, drives the community assembly of endemic *Caridina* shrimps in Lake Poso, revealing a critical overlap between high habitat suitability and human disturbance that necessitates targeted conservation planning for this ancient lake ecosystem.
This study identifies soil bacterium *Bacillus* sp. MS-7 as an efficient producer of polyhydroxybutyrate (PHB) using apple peels as a substrate, while also validating a novel, eco-friendly sonication-assisted extraction method and confirming the chromosomal inheritance of the biosynthetic trait.
This study demonstrates that Metformin reduces tau hyperphosphorylation and ameliorates neurodegeneration in specific tauopathy models by modulating AKT and AMPK signaling and maintaining phosphatase activity, while revealing that these therapeutic effects are independent of total tau levels and autophagic status, which are instead influenced by diet and sex.