5760 papers
This study demonstrates that OJIP chlorophyll a fluorescence profiling can detect pre-symptomatic photosynthetic disruptions in common bean as early as one day after inoculation with Cowpea mild mottle virus, offering a rapid, non-destructive tool for distinguishing tolerant from susceptible genotypes in breeding programs.
This study reveals that high temperatures inhibit anthocyanin accumulation in blood oranges by inducing the ubiquitin ligase CsMIEL1 to ubiquitinate and degrade the transcription factor CsMYB113, thereby suppressing the expression of key biosynthetic genes required for pigment production.
This study reveals that mangrove killifish embryos exhibit a unique, neuronally mediated, and reversible cardiac arrest in response to physical disturbance, offering new insights into conserved neurocardiac mechanisms and establishing the species as a model for studying heart rhythm regulation.
This study demonstrates that a 67-bp variable duplication in the bovine *ADIPOQ* promoter functions as a copy number-dependent repressor of gene expression via a HES5-responsive motif and is significantly associated with variations in fat-related carcass traits in Gaoqing Black cattle.
This study demonstrates that converting pangenome graphs to VCF format causes a significant, size-dependent loss of structural variant allele counts due to fragmentation during bubble decomposition, a problem that can be avoided by directly counting alleles from haplotype path traversals instead.
This study utilizes multimodal imaging and multi-omics analyses in macaques to demonstrate that a single dose of psilocybin induces lasting functional network reorganization, enhanced energy metabolism, and neuroimmune modulation characterized by anti-inflammatory shifts and extracellular matrix remodeling in the primate brain.
This study characterizes a novel chromosomally encoded OXA-12-like β-lactamase variant (blaOXA-1433) and a new sequence type (ST3591) in Aeromonas veronii isolated from ready-to-eat oysters, highlighting the role of seafood as a reservoir for emerging antibiotic resistance determinants.
This study identifies a set of high-confidence gene expression changes in multiple sclerosis white matter through a meta-analysis of a 468-gene detoxification panel across three cohorts, yet finds that these panel genes are not significantly enriched for differential expression compared to the rest of the transcriptome and that the findings represent postmortem transcript associations rather than established mechanisms like ferroptosis.
This study demonstrates that the ethanolic leaf extract of *Emilia coccinea* exhibits hepatoprotective effects against doxorubicin-induced liver injury in Wistar rats, evidenced by significantly reduced AST and ALT levels and improved liver histology compared to the untreated control group.
This study presents a modular living immunotherapeutic strategy using tumor-tropic *E. coli* engineered to surface-display adenosine deaminase and interleukin-12, which locally converts immunosuppressive adenosine into T-cell-fueling inosine while simultaneously stimulating immune responses to effectively control diverse hematologic and solid tumors.