4127 papers
This study demonstrates that mandible shape in Icelandic Arctic foxes exhibits significant phenotypic divergence driven by ecotypic dietary differences between coastal and inland habitats, as well as by early-life population density conditions that manifest morphologically as the animals age.
This study demonstrates that while insulin-derived fibrils with and without phenolic preservatives share similar structural properties, the presence of preservatives significantly enhances fibril-induced cytotoxicity and ROS production in macrophages, revealing distinct immunomodulatory mechanisms that underscore the need for strategies to improve the biocompatibility of insulin infusion devices.
This study reveals that prolonged cold stress induces severe neuro-oxidative damage and metabolic reprogramming in the juvenile fourfinger threadfin brain, characterized by initial antioxidant suppression followed by late-stage failure, lipid peroxidation, and disrupted amino acid and glycerophospholipid metabolism, ultimately offering critical insights for improving cold tolerance in aquaculture.
This study demonstrates that the primate hippocampus contains distinct, coexisting populations of position, view, and conjunctive cells, resolving the debate over species differences by showing that robust rodent-like place codes exist in primates but were previously overlooked due to methodological and task-related factors.
This study demonstrates that deoxyshikonin (3 µM) protects human umbilical vein endothelial cells from high-glucose-induced injury by restoring angiogenic capacity and modulating the expression of key downstream effectors, including IFITM1, THY1, CCBE1, CCL2, and ENTPD1, through pathways involving extracellular matrix organization, inflammation, and angiogenesis.
This study introduces an "Akinator"-inspired experimental paradigm to demonstrate that neural signatures of binary mental agreement and disagreement, including P3a and N270 components, are significantly modulated by feedback, stimulus context, and presentation sequence, thereby advancing the development of BCI communication and verification systems.
This study demonstrates that risk-adaptive decision-making relies on low-dimensional neural computations that segregate safe and risky states, a mechanism identified through deep reinforcement learning agents and validated by similar dynamical patterns in human neuronal recordings.
This study demonstrates that miR-5193 promotes ferroptosis and suppresses ovarian cancer progression by directly targeting and repressing the E3 ubiquitin ligase BBAP, which subsequently stabilizes PRNP by preventing its ubiquitination-mediated degradation.
This study utilizes resting-state EEG data from the MODMA dataset to demonstrate that Major Depressive Disorder is characterized by specific alterations in signal complexity and functional network topology, particularly involving reduced integration and increased segregation in frontal, parietal, temporal, and occipital regions, thereby establishing these metrics as promising objective neurophysiological biomarkers for the disorder.
This study utilizes bibliometric analysis of 845 Web of Science publications from 2014 to 2025 via ITGInsight to map the global research landscape of spider venom, identifying leading contributors and core journals while highlighting a shift toward molecular mechanisms and medical applications alongside a comprehensive review of its chemical constituents and pharmacological potential.