4194 papers
This study demonstrates that a single early-life herbivory event significantly increases nodule biomass and allocation in African savanna woody legumes, particularly in *Vachellia sieberiana*, suggesting that young saplings adapt to browsing pressure by prioritizing nitrogen-fixing mutualisms.
This bibliometric and network analysis of 2,862 global publications from 1913 to 2026 maps the evolution of Branchiopoda research, revealing a shift from early pharmacological and bioassay studies toward contemporary themes in molecular systematics, conservation, and climate-related ecology, with the United States, China, and Belgium emerging as leading contributors.
This study employs a structure-guided repurposing workflow to identify and prioritize specific SARS-CoV-2 antiviral candidates, such as J08_67 and J08_51, as potential inhibitors of key Mpox viral enzymes through rigorous computational docking, molecular dynamics simulations, and pharmacokinetic profiling.
An analysis of the SEA-AD atlas reveals that while broad metabolic transcriptional programs in human microglia are organized by cell state, they do not exhibit robust monotonic associations with regional Alzheimer's disease pathological burden across donors.
This paper synthesizes evidence that *Lotmaria passim* serves as a robust experimental model for understanding trypanosomatid adaptation to the insect gut, demonstrating that membrane homeostasis, protein trafficking, and extracellular functions are more critical for host colonization than motility alone.
This study reveals that seven years of nutrient enrichment in alpine meadows reshapes soil nematode communities through distinct trait-based and abundance-based pathways, where balanced nitrogen and phosphorus addition uniquely mitigates diversity loss and stabilizes the food web by altering body size and abundance across trophic levels.
This study demonstrates that Clusterin, a molecular chaperone, is upregulated and co-localized with α-Synuclein aggregates in the substantia nigra of Parkinson's disease patients, suggesting it initially acts protectively but becomes trapped in Lewy bodies as the disease progresses, thereby identifying it as a key mediator of proteostasis failure and a potential therapeutic target.
This study demonstrates that the CDT binary toxin of *Clostridioides difficile*, whose expression is induced by hypoxia via LuxS-dependent regulation, drives neutrophil activation and exacerbates inflammatory tissue damage in the hypoxic colonic environment characteristic of severe infections.
This systematic review of 75 single-cell RNA sequencing studies on five human oncoviruses reveals that while no universal host-gene signature exists, recurring virus-host programs involve complex immune interactions and viral transcript associations that vary by context, highlighting the need for rigorous study designs to develop reproducible biomarkers.
This study characterizes chromatin accessibility and its genetic regulation in the lactating bovine mammary gland by integrating ATAC-seq and RNA-seq data from 199 cows to identify thousands of caQTLs and eQTLs, revealing how specific transcription factors and chromatin states mechanistically modulate gene expression.