3724 papers
This study reveals that European brown hare populations at the southern edge of their range in Catalonia remain stable at low densities primarily due to intrinsic density-dependent regulation, while disease outbreaks and habitat favourability exert negligible influence on short-term population growth.
This study characterizes the 2024 dengue outbreak in Togo as the result of a single viral introduction of the DENV-1 genotype III lineage A.2 from Tanzania around early 2020, which subsequently spread extensively through local and regional transmission facilitated by environmental and human mobility factors, while highlighting critical gaps in West African genomic surveillance.
This study integrates multi-omics analyses and in vivo validation to reveal that the TNIP1/ABIN1 protein defines a neuroprotective microglial subpopulation which suppresses NF-κB-driven neuroinflammation via the App-Trem2 pathway after ischemic stroke, offering a novel therapeutic target that can be pharmacologically activated by Genistein-3′-sodium sulfonate.
This paper describes *Astragalus kharazmii*, a new species from eastern Iran within section *Caprini*, by integrating morphological, micromorphological, molecular phylogenetic, and biogeographic evidence to distinguish it from related taxa, estimate its Late Miocene–Early Pliocene divergence, and provisionally classify it as Data Deficient due to limited distribution data.
This study demonstrates that the activation of the mTOR-TFEB-autophagy–lysosome axis enhances lysosomal capacity and autophagic flux to limit pathological prion protein accumulation during prion infection, suggesting TFEB activation as a potential therapeutic strategy.
This study provides the first genetic evidence that specialized cave-dwelling isopods can successfully recolonize surface habitats and retain evolutionary flexibility, challenging the paradigm that extreme life-history specialization inevitably leads to evolutionary dead ends.
This study demonstrates that fermented taro (poi) acts as a natural synbiotic that strengthens intestinal barrier integrity, suppresses inflammatory signaling, and reshapes gut microbiota to enhance beneficial metabolic functions, highlighting its potential as a functional food for intestinal health.
This study assessed the genetic diversity of four montane bamboo species in the Central and North-Western Himalayan region using molecular markers, revealing significant polymorphism and providing critical data to inform conservation and breeding strategies for these threatened resources.
The paper introduces PS-HTI, a novel pair-conditioned enclosing-subgraph learning framework that significantly outperforms the existing HTINet2 benchmark in herb-target prediction by leveraging query-edge-masked subgraph construction and dual-anchor representation to better capture the multi-constituent nature of medicinal herbs.
This study establishes the first validated rumen-specific MALDI-TOF MS database and an automated spectral processing workflow, which significantly enhance the accuracy, reproducibility, and taxonomic resolution of identifying previously underrepresented ruminal bacteria and archaea compared to commercial databases.