1432 papers
This study presents the first genome-wide identification and comprehensive bioinformatic characterization of the eight RcGH3 genes in *Rosa chinensis*, elucidating their phylogenetic relationships, genomic distribution, conserved motifs, and potential regulatory mechanisms to establish a foundation for future functional research.
The paper introduces CommuSpace, a computational framework that redefines multicellular tissue organization by mapping cells into a communication space based on ligand–receptor interactions, thereby revealing emergent "communication ecosystems" as a fundamental higher-order layer of tissue architecture that transcends traditional cell identity and spatial niche classifications.
This study provides the first comprehensive architectural characterization of the threatened West African timber species *Khaya senegalensis* and *Pterocarpus erinaceus*, revealing their distinct developmental models and plastic responses to environmental gradients to establish a scientific basis for optimizing their conservation, reforestation, and sustainable management.
The paper introduces EEG-to-Report, a browser-based framework that streamlines clinical EEG annotation by integrating multi-format data ingestion, interactive visualization, and automated feature extraction to generate structured feature–text pairs for training multimodal language models and drafting automated clinical reports.
This paper introduces the Gait Perturbation Burden (GPB), an unsupervised, consensus multifeature index that leverages individualized wearable inertial baselines to specifically detect locomotor perturbations with significantly reduced false positives during normal walking compared to single-feature or amplitude-only methods.
This study demonstrates that synonymous codon usage in *Platycerium* plastomes retains phylogenetic signals across geographic lineages while revealing a conserved, evolutionarily significant deficit of CpG dinucleotides at codon boundaries that persists despite strict controls for sequence composition and codon counts.
This study applies Structural Equation Modeling (SEM) to psoriasis transcriptomic data, revealing a statistically significant structural relationship between epigenetic dysregulation and disease pathology that is strongly characterized by the downregulation of the long non-coding RNA H19.
This study provides the first comprehensive characterization of human pre-miRNA terminal loop regions, revealing distinct sequence architectures defined by specific length distributions, positional nucleotide biases, and enriched motifs that may influence miRNA biogenesis and protein interactions.
This empirical study demonstrates that the pretrained gene-token embeddings of the scGPT model inherently encode physical protein-protein interaction structures, as evidenced by significantly higher cosine similarity between interacting gene pairs compared to matched non-interacting controls across multiple databases.
This paper empirically demonstrates that the static gene-token embedding space of the scGPT foundation model encodes detectable, albeit moderate, information about known physical protein-protein interactions, as evidenced by significantly higher cosine similarities and interaction prediction metrics for interacting gene pairs compared to non-interacting controls.