🧬 biology

Measuring children's associative divergent ability through drawings and semantic similarity

This paper proposes a novel, data-driven method for measuring children's associative divergent thinking by converting drawings into semantic information via large language models to calculate semantic similarity, revealing key patterns in thematic distribution, the influence of priming and age, and minimal gender differences.

Jing-jing Zhang, Yi Zhang, Fan Wei, Yu Zhai, Hao-ran Li, Tong Liu, Jia-bao Wu, Meng Zhang, Jia-yao Wang, Ying Zhao, Laip (…)2026-07-23
🧬 biology

PARP1–FOXO3a–Depp1 signaling axis Drives Blood–Brain Barrier Disruption Under Chronic Cerebral Hypoperfusion by Triggering Excessive Autophagy Initiation

This study reveals that chronic cerebral hypoperfusion triggers blood–brain barrier disruption and vascular cognitive impairment through a PARP1–FOXO3a–Depp1 signaling axis that drives excessive autophagy initiation, a mechanism that can be effectively targeted by the PARP1 inhibitor Olaparib.

Xiaoyi Ji, Wenjian Hu, Yisheng Wang, Maosen Huang, Anqi Li, Xiaodi Hao, Ningning Che, Zhenxiang Zhao, Ruihua Sun, Jiewen (…)2026-07-23
🧬 biology

Static DNA-Methylation Burden Discriminates Hematologic-Malignancy Subtypes but Does Not License Per-Patient Trajectory Inference: A Public-Cohort Analysis and an Identifiability Framework

This study demonstrates that while static DNA-methylation burden and entropy can effectively classify hematologic malignancy subtypes and distinguish them from healthy donors using public cohort data, such cross-sectional measures are insufficient for inferring individual disease trajectories, necessitating prospective serial sampling to validate lead-time estimation.

Frederic Scheer2026-07-23
🧬 biology

Rapid bee inventories for monitoring changes in Cerrado assemblages: Complementary traps for multiple taxa and trait groups

This study demonstrates that combining blue cup, scent-bottle, and Malaise traps provides a comprehensive and cost-effective framework for rapid bee inventory and monitoring in the Brazilian Cerrado, revealing high species richness and the critical conservation value of Brasília National Park.

José Vinicius, Alexandre S. Barbosa, César N. M. Teixeira, Helena Moriani, Rafael Chagas, Antonio J. C. Aguiar2026-07-23