4413 papers
Based on citizen science data from 2016 to 2025, this study reveals that urban conflicts between humans and jaguars or pumas in Brazil are relatively rare but concentrated in the Southeast and Central-West regions, with pumas being the primary species involved, highlighting the urgent need for targeted management strategies to mitigate human-wildlife overlap.
This study demonstrates that sustained low-intensity direct current electric fields induce a voltage-dependent, biphasic apoptotic response in HeLa cells via controlled membrane permeabilization, characterized by a hormetic viability recovery at intermediate doses and a shift from early to late apoptosis at higher intensities, while largely suppressing necrosis.
This study demonstrates that low-intensity direct current induces colloid-osmotic swelling in HeLa cells, which acts as an upstream physical trigger distorting mitochondrial function to initiate regulated electro-apoptosis rather than necrosis, offering a new biophysical framework for optimizing bioelectric cancer therapies.
This study utilized Response Surface Methodology with a Box-Behnken design to optimize a complex lyoprotectant formulation of skim milk, sucrose, and glycerol, successfully achieving a high viability rate of 85.73% for lyophilized *Penicillium chrysogenum* ACCC 30395 conidia, which closely matched the model's predicted value.
This study utilized comparative in vivo transcriptome analysis of *Beauveria bassiana* strain GHA at distinct infection stages to identify upregulated virulence genes involved in cuticle penetration and hemocoel colonization during its infection of the beneficial predator *Nesidiocoris tenuis*, offering a strategy to address the fungus's unintended toxicity to this biological control agent.
This bioinformatics study reveals that RAD51C is significantly overexpressed in cervical cancer and linked to DNA repair and cell-cycle pathways, yet it does not serve as a significant prognostic marker or correlate with major immune checkpoint genes despite showing specific associations with certain immune cell infiltrates.
This study demonstrates that neurexin and neuroligin deficiency in *C. elegans* causes widespread transcriptional reprogramming affecting diverse pathways beyond synaptic function, thereby linking molecular dysregulation to the observed developmental, behavioral, and neuromorphological abnormalities.
This study defines the clinical and radiological spectrum of a variable leukodystrophy caused by biallelic SUPV3L1 mutations, demonstrating that the loss of this mitochondrial degradosome component leads to neurodevelopmental impairment and microcephaly through the dysregulation of type I interferon signaling.
This study identifies PTEN downregulation and NOTCH1 upregulation as conserved molecular signatures of oral squamous cell carcinoma across distinct Indian populations (Gujarat and Telangana), suggesting their potential as robust, geography-independent biomarkers for the disease.
This study identifies phosphorylation of ribosomal protein S6 at Ser235 and increased IL-6 release in peripheral blood mononuclear cells as a distinct inflammatory signature that correlates with clinical severity and distinguishes manifesting Parkinson's disease from non-manifesting states across both idiopathic and LRRK2-associated forms.