q-bio papers | Gist.Science

Entropy-Based Indicators of Critical Transitions in Power-Law Networks Under Progressive Node Removal

This paper proposes and validates a smoothed successive Kullback-Leibler divergence of degree distributions as an effective early-warning signal for critical transitions in power-law networks, demonstrating its ability to detect impending collapse earlier than traditional connectivity measures under random node removal while providing immediate disruption summaries under targeted attacks.

Zachary Alexander Kraehling2026-07-08

🧬 biology

Correlation of Prefrontal Cortex Connectivity and Vestibulo-Ocular Reflex with Motor Skills and Functional Performance in Children with Cerebral Palsy

This cross-sectional study of children with spastic diplegic cerebral palsy reveals that while altered prefrontal cortex EEG activity correlates with social function, vestibulo-ocular reflex parameters do not directly associate with motor or functional performance, highlighting the multifactorial nature of motor impairment in this population.

Denesa Nagpal¹, Priya Chauhan, Susmita Pandey2026-07-08

🧬 biology

Metagenomic characterization of viral communities across coastal matrices highlights bivalves as integrative sentinel hosts within a One Health framework

This study utilizes metagenomic sequencing across coastal water, bivalves, and marine mammals to demonstrate that filter-feeding bivalves serve as effective integrative sentinel hosts for monitoring diverse and dynamic viral communities, thereby supporting One Health surveillance and early detection of zoonotic risks.

Katie Vigil, Tiong Gim Aw2026-07-08

🧬 biology

GenPTM: A Generalizable Framework for Protein Post-Translational Modification Information Extraction from the Scientific Literature

GenPTM is a generalized, BiomedBERT-based framework that overcomes the limitations of PTM-specific tools by using a unified text representation strategy to accurately extract protein modification events and sites from scientific literature across a wide range of PTM types.

Shovan Bhowmik, Karen Ross, Chuming Chen, Cathy Wu, K. Vijay-Shanker2026-07-08

🧬 biology

Acute severe hypoxia induces prolonged cardiac transcriptomic remodeling despite rapid functional recovery

Although adult zebrafish hearts rapidly recover their electrical function following acute severe hypoxia, transcriptomic analysis reveals that significant molecular remodeling and stress responses persist for at least seven days, demonstrating that functional recovery does not equate to immediate molecular normalization.

Steven Williams, Raymond Hendricks, Warren Burggren2026-07-08

🧬 biology

First complete mitogenome of Clinostomum dimorphum reveals conserved genomic features and phylogenetic relationships within Clinostomidae

This study presents the first complete mitochondrial genome of the Amazonian fish parasite *Clinostomum dimorphum*, generated via hybrid sequencing to resolve complex regions, and reveals conserved genomic features alongside lineage-specific evolutionary patterns that clarify phylogenetic relationships within the Clinostomidae family.

Aarón Mondragón-Martínez, Jhon D. Chero, Rosa Martínez-Rojas, Julio Solis Sarmiento, David Lopez, Celso L. Cruces, Luis (…)2026-07-08

🧬 biology

NatCodon: protein-structure-informed de novo codon sequence design for efficient protein expression

NatCodon is a generative model that leverages protein structural information to optimize codon sequences for co-translational folding, significantly outperforming existing frequency-based methods by strategically deploying rare codons to enhance soluble protein yields and enable the expression of previously intractable targets.

Sheng Ye, Yujie Qin, Shen Ge, Kaiyue Wang, Mengchen Pu, Zilin Lyu, Zibo Cui, Fenghui Shi2026-07-08

🧬 biology

Deep Learning-Based Animal Footprint Analysis for Species Recognition and Injury Detection

This paper presents a unified deep learning system that utilizes ConvNeXt-V1 to automatically classify animal species and detect foot injuries from static track images, achieving high accuracy in a 12-class setting and demonstrating that injury detection is particularly effective when decoupled from species discrimination.

Pranav Bharadwaj2026-07-08

🧬 biology

Maternal diet-induced excess adiposity programs multisystem vulnerability that is unmasked by postnatal infection challenge

This study demonstrates that maternal high-fat diet-induced excess adiposity programs latent, sex-specific vulnerabilities in the immune, intestinal, and metabolic systems of offspring, which are unmasked as multisystem dysfunction following a postnatal *Streptococcus pneumoniae* infection.

Tatiane Ribeiro, Anastasia Warmington, Erica Yeo, Christian Bellissimo, Brianna Kennelly, Braeden Cowbrough, Patrycja Ja (…)2026-07-08

🧬 biology

Coordination-Sphere Perturbations Partition Catalytic Bias Control in a Thermostable [FeFe]-Hydrogenase

This study reveals that the catalytic bias of the thermostable [FeFe]-hydrogenase Tk HydA2 is governed by a distributed regulation model where distinct perturbations in the first- and second-coordination spheres of its iron-sulfur clusters synergistically modulate kinetic, electrostatic, and redox-relay effects to fine-tune the enzyme's reversible H2 interconversion.

Zhiguang Zhu, Yuanming Wang, Weisong Liu, Zepeng Kang, jiajun liu, Jing-Xin Li, Lu Yu, Lingling Zhang2026-07-08

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