3726 papers
This bioinformatics study analyzes cervical cancer gene expression profiles to identify 155 differentially expressed genes and six hub genes (CRNN, SPINK5, GBP6, IFI44, CDKN2A, and CXCR4), proposing them as potential biomarkers for early diagnosis and targeted therapy to improve patient outcomes.
This paper presents and validates a distribution-informed method that accurately estimates normalized electromyogram (EMG) envelopes from unnormalized signals without requiring time-consuming maximal voluntary contraction (MVC) calibration tasks.
Exposure of airway basal cells to double-stranded RNA triggers a TLR3-mediated biphasic response that prioritizes antiviral defense over epithelial differentiation and induces chronic inflammation, ultimately impairing airway barrier formation and function.
This study demonstrates that under tropical outdoor conditions in Thailand, the cultivation environment exerts a significantly larger influence on the growth performance and CO2 fixation of Chlorella sp. in photobioreactors than the choice between flat panel and tubular geometries.
This study demonstrates that combining vaccine-induced anti-PfRH5 antibodies with early-acting invasion inhibitors, particularly heparinoids like heparin and sevuparin, synergistically enhances the inhibition of *Plasmodium falciparum* growth, offering a promising chemico-vaccine strategy to improve malaria vaccine efficacy.
Five years after the 2016 Madeira wildfires, island bat activity was found to be dynamic and species-specific, with higher overall activity at burned sites primarily resulting from population declines in unburned areas rather than fire-induced increases, underscoring the critical need for post-fire management that preserves heterogeneous landscapes with unburned refugia.
This scoping review highlights that methodological heterogeneity and insufficient reporting of analytical sensitivity in culture-based intervertebral disc microbiology studies likely contribute to divergent findings regarding bacterial infections in chronic low back pain, underscoring the need for standardized, quantitative protocols in future research.
This study demonstrates that airborne environmental nucleic acid (eNA) analysis serves as a comprehensive, pathogen-agnostic surveillance tool for monitoring animal, microbial, and viral communities at One Health interfaces, effectively complementing traditional methods like camera trapping, bioacoustics, and invertebrate-derived DNA to assess disease spillover potential.
This study reveals that captive sloth bears in India suffer from gut dysbiosis and a high accumulation of multi-drug antimicrobial resistance, particularly within Enterobacteriaceae species, driven by captivity-associated stressors and the presence of mobile genetic elements that facilitate resistance dissemination.
This study utilizes stable isotope analysis to reveal that Sooty and Bridled Terns in the Mexican Caribbean exhibit seasonal trophic segregation, with Sooty Terns occupying a broader niche during the pre-laying period and limited overall overlap throughout the annual cycle, thereby facilitating their sympatric coexistence.