5841 papers
This paper establishes a closed-form phagocyte-recruitment threshold that defines a structurally robust treatment window, separating bacterial clearance from chronic carriage and immunopathology within a minimal two-dimensional model of host-pathogen dynamics.
This study reveals that fish exploit vortex wakes to save energy through a Kármán gait characterized by a phase-locked, near-resonant body motion where passive compliance and frequency matching enable stable entrainment, with active regulation concentrated in the anterior body.
This study introduces Trait2Myco, a Random Forest-based machine-learning framework that successfully predicts plant responsiveness to arbuscular mycorrhizal fungi by integrating key leaf and root functional traits with precipitation data, revealing that resource-acquisitive trait syndromes and specific environmental conditions are the strongest drivers of mycorrhizal growth response.
This study demonstrates that the spatial arrangement of positive charges in meso-substituted porphyrin photosensitizers, specifically the presence of adjacent charges in asymmetric dicationic structures, is a critical molecular determinant for enhancing bacterial photoinactivation by facilitating deeper membrane penetration and oxidative damage, surpassing the efficacy of symmetric regioisomers despite similar lipophilicity and singlet oxygen yields.
This study utilizes comparative genomics of clinical Acinetobacter baumannii isolates from a Brazilian ICU to reveal that multidrug and extensively drug-resistant phenotypes are driven by a multifactorial combination of clonal diversity, accessory gene burden, chromosomal mutations, and taxonomic complexity within the ACB complex.
This study reanalyzes single-cell data from the mouse medial vestibular nucleus following unilateral vestibular loss to demonstrate that sequencing depth significantly biases differential expression results, revealing that the acute response is driven by a microglial Cd14/Tlr2 program rather than IL-1 receptor activation.
This study establishes a standardized, optimized protocol for secretome metabolomics by systematically evaluating solvent systems and preparation techniques to enhance metabolite detection and reproducibility, thereby enabling harmonized analysis of metabolic crosstalk in the tumor microenvironment.
This cross-sectional study of 87 clinical Klebsiella pneumoniae isolates from Egyptian ICUs reveals that carbapenem resistance and the carriage of mrkD, fimH, and wcaG genes are independently associated with a higher likelihood of biofilm formation.
This study demonstrates that seed biopriming with fungal endophytes, particularly *Daldinia eschscholtzii*, effectively enhances cotton defense against *Rhizoctonia solani* by coordinately upregulating pathogenesis-related enzymes like chitinase and β-1,3-glucanase and modulating key biochemical defense responses.
This study challenges the notion that thermophilic microorganisms are dispersal-limited by demonstrating through genomic and experimental evidence that diverse thermophiles from isolated Antarctic geothermal sites are globally cosmopolitan, capable of rapid recolonization, and can disperse via volcanic events and atmospheric conditions.