1498 papers
This study demonstrates that dried menstrual blood collected via Q-Pads and stored at room temperature for over two years is a viable, minimally invasive biospecimen for genome-wide DNA methylation profiling and accurate epigenetic age estimation.
This study reveals that archaeal transcriptional regulation is far more diverse than previously thought by identifying 250 non-canonical DNA-binding protein families across a phylogenetically balanced genome panel, thereby expanding the known regulatory landscape beyond the nineteen canonical families and providing a ranked set of experimentally testable hypotheses for their functions.
This study demonstrates that a brief 10-minute mindfulness induction enhances emotional attentional regulation by reducing processing delays for negative stimuli and increasing attention allocation to positive distractors within the Emotional Attentional Blink paradigm.
This study presents an end-to-end deep learning framework for automated mosquito egg detection and counting in vector surveillance that achieves high precision and reliable performance across diverse real-world conditions by leveraging a standardized scanning protocol, expert-guided annotation, and a synthetic data generation pipeline trained exclusively on synthetic images.
This study employs computational in silico screening to identify 11-O-Galloyl bergenin and related Himalayan phytochemicals as novel, high-affinity inhibitors of the oncogenic chaperone AGR2, establishing a preliminary structure-activity relationship for future experimental validation in cancer therapeutics.
This paper proposes the Resonance of Closed Neural Network Geometries (RCNNG) framework, which posits that perception and consciousness emerge from stable resonant attractors in recurrent neural circuits, where perceptual stability and subjective experience ("innergence") arise from the mapping of input-driven closed neural geometries to their intrinsic resonant identities rather than their physical structures.
This study demonstrates that maternal influenza infection triggers fibrinogen accumulation and microglial oxidative stress in the fetal mouse brain, leading to sex-biased apoptosis of neural progenitors, particularly in males, which may underlie adverse neurodevelopmental outcomes.
This study analyzes craniometric data from 335 skulls across four historical periods in Azerbaijan to identify epochal morphodynamic changes and develop discriminant functions for the preliminary chronological classification of human skulls.
This study demonstrates that the Antarctic bacterium *Flavobacterium azizsancarii* and the broader *Flavobacterium* genus exhibit a statistically significant, composition-adjusted excess of intergenic small open reading frames (sORFs) compared to null models, suggesting a genus-wide reservoir of potential sORFs rather than a strain-specific adaptation, though their functional translation and cold-adaptive roles remain unconfirmed.
This study evaluates the performance variations of RNaseR enzymes from four different vendors on RNA vaccine drug substance, demonstrating that digestion efficiency is significantly influenced by vendor source, incubation conditions, and buffer composition, with optimized formulations notably enhancing linear RNA degradation.