4605 papers
This study reveals that BHET-hydrolyzing enzymes are widespread in marine environments and function as a crucial downstream component of a community-based pathway for PET plastic degradation, where diverse microbes collaboratively complete the breakdown process through a division of labor.
Green-synthesized zinc oxide nanoparticles derived from *Senna auriculata* flowers exhibit significant antioxidant, antimicrobial, and mitochondria-mediated anticancer activities, demonstrating their potential for biomedical and therapeutic applications.
This paper argues that the Western gut microbiome, despite appearing healthy, possesses a hidden resilience deficit characterized by low functional redundancy and reliance on keystone taxa, making it structurally fragile and prone to abrupt, irreversible shifts when faced with perturbations.
GlyGen is a comprehensive knowledgebase that harmonizes and integrates fragmented glycan, protein, and gene data into a unified, ontology-driven model to facilitate the discovery of novel biological connections and advance glycoscience within the broader biomedical ecosystem.
This study presents a novel graphene oxide–gelatin–calcium integrated Transwell platform that enables non-destructive, bidirectional electrochemical monitoring of oxygen dynamics to spatially resolve the asymmetric progression of epidermal differentiation in keratinocyte cultures.
This study demonstrates that long-term, gene-free photostimulation using a far-red absorbing organic semiconductor (PCPDTBT) effectively promotes the comprehensive maturation of human pluripotent stem cell-derived cardiomyocytes across transcriptional, functional, structural, and metabolic levels without causing phototoxicity, thereby enhancing their utility for disease modeling and therapeutic applications.
This study utilizes untargeted cord blood metabolomics to reveal that neonates with gastroschisis exhibit a distinct metabolic profile characterized by significant alterations in lipid metabolism, including reduced free fatty acids and disrupted bile acid pathways, which may underlie their susceptibility to gastrointestinal complications.
This study demonstrates that in regenerating Atlantic Forest vegetation, early community reorganization is driven by recruitment dynamics and vertical stratification—particularly in the lower stratum—rather than immediate floristic turnover, suggesting that structural changes precede detectable compositional shifts during ecological succession.
This longitudinal multimodal MRI and imaging genetics study demonstrates that both short-term and long-term social media exposure induce distinct functional and structural brain plasticity, respectively, with the magnitude of these neuroimaging changes varying according to habitual usage patterns and individual APOE and BDNF genotypes.
This study reveals that exogenous serotonin enhances the antitumor efficacy of anti-PD-1 therapy by inducing TGM2-mediated serotonylation of STAT1 in CD8+ T cells, which remodels mitochondrial dynamics to suppress fission and promote fusion, thereby boosting T cell function.