3726 papers
This study reveals that mushroom fruiting bodies possess bona fide tissues regulated by the co-option of ancient mating pheromone and receptor genes, demonstrating how selection can drive the convergent evolution of complex multicellularity across organisms with fundamentally different cellular architectures.
This study employs multiscale QM/MM simulations and non-Markovian dynamics to demonstrate that the honeybee *Apis mellifera* rhodopsin utilizes quantum coherence and a lipid-protein error-correcting reservoir to achieve near-perfect sensory transduction fidelity under thermal stress, significantly outperforming conventional electrostatic models.
This study demonstrates that four distinct diatom species with varying symmetries and ultrastructures can focus visible light through side-illumination, generating diffraction-driven photonic jets similar to those found in artificial mesoscale dielectric structures.
This study provides a morphological and meristic characterization of five commercially important decapod crustaceans (three *Macrobrachium* prawns and two *Penaeus* shrimps) from the Barisal Deltaic Region of Bangladesh to establish a taxonomic baseline for sustainable fisheries management.
This study reveals that advanced nasopharyngeal carcinoma bypasses extracellular inflammatory stimuli to drive progression through a cell-intrinsic, ligand-independent signaling cascade initiated by latent EBV-LMP1, which is uniquely identifiable by a specific transcriptomic signature of host TRAF1 induction, TRADD repression, S100 family collapse, and EGFL8-CDK-mediated epithelial-to-mesenchymal transition.
This study identifies FDB020301 as a promising next-generation anti-HIV lead by integrating XGBoost-based virtual screening, ADMET profiling, molecular docking, and molecular dynamics simulations to demonstrate its superior binding affinity and stability against the CCR5 receptor compared to the clinical drug Maraviroc.
This study reveals that selective disinhibition of somatostatin neurons in the medial prefrontal cortex confers stress resilience in male mice by preserving their transcriptomic stability against chronic stress, a mechanism that is absent in females and distinct from the ventral hippocampal resilience observed in female mice.
This study demonstrates that the Biology First Intelligence (BFI) framework can reconstruct a partial, set-valued latent architecture from the complex genomic data of a single undifferentiated sarcoma case, revealing state-dependent network vulnerabilities and mechanistic hypotheses that extend beyond conventional driver-matching approaches.
This study analyzes LTR retrotransposon profiles across 601 angiosperm genomes to reveal that their distinct, stable landscape emerged gradually over 140 million years, with specific variable lineages and overall patterns closely aligning with the APG IV phylogeny, suggesting a significant role for transposable element activity in angiosperm evolution and taxonomic diversification.
A study of over 10,000 adults reveals that the mental health risks associated with seven different digital technologies are driven by a single general factor of problematic use rather than platform-specific mechanisms, suggesting that apparent differences in harm reflect a shared user vulnerability.