5845 papers
This study utilized 2,294 SNP markers to evaluate the genetic diversity and purity of 87 maize genotypes in Ethiopia, revealing that 64% of inbred lines lacked sufficient purity and required further inbreeding while identifying distinct genetic clusters to enhance breeding efficiency and seed quality control.
This study evaluates six key factors affecting environmental HPV detection in a laboratory setting, concluding that dry polyester swabs combined with dedicated viral transport media offer the most practical approach for molecular recovery, while surface material and ambient temperature are the primary determinants of detectability.
This study successfully adapted and field-validated a pesticide-specific bioindicator for South Korea's Seomjin River by integrating toxicity data from 20 indigenous species, demonstrating that controlling for organic pollution gradients reveals a robust correlation between the index and pesticide exposure that standard diversity metrics cannot detect.
This study demonstrates that personalizing gait biomechanics for lower-limb joint moments using limited subject-specific data is primarily driven by adapting the temporal waveform shape rather than the amplitude, resulting in significant prediction accuracy improvements over population-wide models.
By analyzing scRNA-seq data across multiple cancer types and treatment cohorts, this study infers clone-specific gene regulatory networks to demonstrate that tumor clones exhibit distinct regulatory architectures linked to fitness, where treatment-induced remodeling drives structural divergence yet functional convergence, ultimately revealing conserved and variable regulons associated with patient survival.
This study demonstrates that inflammatory stimuli impair myelin clearance by promoting lipid accumulation in macrophages, a process that can be mitigated by agonists of the nuclear receptors LXR, PPARγ, and RXR, suggesting these receptors as potential therapeutic targets for CNS injuries involving lipid debris.
This study demonstrates that the failure of CRISPRi/a efficacy models to generalize across different guide libraries and cell lines is primarily driven by within-gene label normalization rather than a lack of chromatin features, as retraining with harmonized continuous labels significantly restored transfer performance.
This study characterizes two mango FCA2 genes (MiFCA2-SJ and MiFCA2-JH), demonstrating their nuclear localization, interaction with stress-related proteins, and distinct roles in promoting early flowering under temperature stress and modulating responses to drought and salt via the ABA signaling pathway.
This study demonstrates that while fixed defaults for the number of principal components often work, data-driven optimization is essential for scRNA-seq analysis due to variable optimal ranges across diverse datasets, and it provides practical recommendations for selecting these methods based on a comprehensive evaluation of real and simulated data.
While pollinator abundance and network structure remain resilient and facilitate pollen flow across agricultural landscapes during tropical forest recovery, the full restoration of specialized plant-pollinator interactions and old-growth network complexity is significantly delayed, taking decades to reassemble.