3746 papers
This study successfully established a long-term, metabolically stable callus culture system for the endemic Amazonian species *Deguelia duckeana* that consistently produces bioactive lupane-type triterpenes over a 12-year period, offering a sustainable alternative for harvesting these valuable compounds.
This study in south-eastern Tanzania reveals that *Anopheles funestus* (s.l.) larvae persist year-round in large ground pools and rivers driven by environmental factors rather than physicochemical properties, while validating pictorial surveys as a reliable monitoring supplement but highlighting the current limitations of drone technology due to vegetation canopy cover.
This study demonstrates that combining in vitro transcriptomics with physiologically-based kinetic modeling provides robust and biologically plausible estimates of systemic toxicity thresholds for the herbicide pendimethalin, yielding points of departure comparable to traditional regulatory in vivo values while highlighting that uncertainty in toxicokinetic modeling contributes as significantly to prediction variability as the choice of transcriptomic analysis method.
This study utilizes single-cell RNA sequencing to characterize the transcriptomic heterogeneity of the DWV-infected honey bee cell line AmE-711, revealing its intermediate cellular identity, improved maintenance protocols, and specific host gene expression patterns associated with viral load that may inform future treatment strategies.
This study establishes a robust, universal untargeted metabolomics pipeline capable of simultaneously profiling over 20 types of metabolite modifications in complex plant extracts, which was successfully applied to reveal distinct glycosylation, acylation, and glutathionylation dynamics and identify resistance-associated markers in wheat during Fusarium head blight infection.
This study demonstrates that the specific subtype of Respiratory syncytial virus (RSV-A vs. RSV-B), rather than viral burden, is the primary driver of distinct reorganizations in the pediatric airway microbiome composition.
This phylogenomic study utilizing five universal protein markers and Neighbor Joining analysis suggests that the archaeal species *Thermococcus pelagicus* represents the deepest branching lineage, diverging prior to the common ancestor of Bacteria and Eukaryotes, while placing specific eukaryotic species within the bacterial clade.
This study demonstrates that the insect *Neolithus fasciatus* induces morphologically convergent galls in the distinct floral nectaries and fruit pericarps of *Sapium glandulosum* through extensive tissue reorganization and specific cell wall remodeling, while retaining organ-specific pectic signatures.
By leveraging long-read sequencing and human pangenome assemblies, this study reveals that predicted Z-DNA-forming sequences are associated with elevated mutation densities, particularly for insertions and deletions, across diverse human haplotypes and genomic contexts.
This study demonstrates that the Suaeda liaotungensis transcription factor SlNAC6, which is induced by abiotic stresses and localizes to the nucleus and cytoplasm, positively regulates salt and drought tolerance in transgenic Arabidopsis by enhancing antioxidant enzyme activities, reducing oxidative damage, and upregulating stress-responsive genes.