3746 papers
This controlled experimental study found that moderate-intensity resistance exercise in healthy young adults does not significantly alter prefrontal cortex oxygenation or cognitive performance, despite causing an immediate reduction in middle cerebral artery blood flow velocity.
This study enhances the Minimum Mutation Load model by incorporating cell density as a key parameter, demonstrating that the extended framework accurately reproduces complex in vitro cell survival curves exhibiting low-dose hyper-radiosensitivity and increased radioresistance with precision comparable to the established Induced Repair model.
This study demonstrates that engineering mouse embryonic stem cells to overexpress β-catenin enhances the generation of functional dendritic cells from blood vessel organoids, which effectively alleviate sepsis-induced acute lung injury by restoring pulmonary immune balance and improving survival in a mouse model.
This study demonstrates that *Staphylococcus aureus* isolates from Italian red deer, belonging to clonal complexes 350 and 425, carry inducible prophages harboring the bovine-specific leukocidin genes *lukM/lukF-P83*, highlighting the potential for these virulence factors to spread among cervids and warranting further investigation into related infections in wild and captive deer populations.
This study demonstrates that auditory cues, particularly when combined with neck muscle vibrations that disrupt vestibular feedback, can induce vection and motion sickness in the absence of visual input, with these subjective experiences correlating with measurable changes in heart rate indicative of increased physiological arousal.
This study introduces a physics-inspired spectral framework using singular value decomposition to analyze single-cell transcriptomics data, revealing that murine pancreatic endocrine differentiation involves a transient, low-dimensional commitment bottleneck at the Ngn3-high state followed by asymmetric stabilization of lineage-specific programs.
This paper proposes a process-aware rule for selecting the rank of low-rank temporal network approximations by prioritizing the preservation of causal dynamics like time-respecting reachability and outbreak sizes over traditional variance-based metrics, demonstrating that matrix-optimal compression often fails to capture essential spreading behaviors.
This study demonstrates that dopamine homeostasis serves as a critical physiological link between age-dependent metabolic stress resistance and longevity in *Drosophila melanogaster*, where elevated dopamine levels enhance starvation tolerance and extend lifespan, while dopamine deficiency has the opposite effect.
This study analyzes 284 global *bla*OXA–*mcr* co-carrying strains to reveal a complex, cross-border transmission network driven by synergistic plasmid–clone co-evolution, highlighting an urgent need for One Health surveillance to address the threat of dual last-resort antibiotic resistance.
This study presents a genome-based framework combining metagenomics and machine learning to predict survival-relevant microbial traits in spacecraft cleanrooms, demonstrating that functional profiling offers a more accurate risk assessment for icy ocean worlds than traditional taxonomy-based or spore-focused methods.